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CSF-1 and Notch signaling cooperate in macrophage instruction and tissue repair during peripheral limb ischemia

Ischemia causes an inflammatory response featuring monocyte-derived macrophages (MF) involved in angiogenesis and tissue repair. Angiogenesis and ischemic macrophage differentiation are regulated by Notch signaling via Notch ligand Delta-like 1 (Dll1). Colony stimulating factor 1 (CSF-1) is an essen...

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Detalles Bibliográficos
Autores principales: Kapanadze, Tamar, Gamrekelashvili, Jaba, Sablotny, Stefan, Kijas, Dustin, Haller, Hermann, Schmidt-Ott, Kai, Limbourg, Florian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484478/
https://www.ncbi.nlm.nih.gov/pubmed/37691936
http://dx.doi.org/10.3389/fimmu.2023.1240327