Cargando…

Changes in antioxidant status and DNA repair capacity are corroborated with molecular alterations in malignant thyroid tissue of patients with papillary thyroid cancer

Introduction: Papillary thyroid cancer (PTC) accounts for approximately 80% of all thyroid cancer cases. The mechanism of PTC tumourigenesis is not fully understood, but oxidative imbalance is thought to play a role. To gain further insight, this study evaluated antioxidant status, DNA repair capaci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eng, Zing Hong, Abdul Aziz, Azlina, Ng, Khoon Leong, Mat Junit, Sarni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484572/ https://www.ncbi.nlm.nih.gov/pubmed/37692064 http://dx.doi.org/10.3389/fmolb.2023.1237548

Ejemplares similares

Whole-exome sequencing and bioinformatic analyses revealed differences in gene mutation profiles in papillary thyroid cancer patients with and without benign thyroid goitre background
por: Eng, Zing Hong, et al.
Publicado: (2023)

Analyses of antioxidant status and nucleotide alterations in genes encoding antioxidant enzymes in patients with benign and malignant thyroid disorders
por: Ramli, Nur Siti Fatimah, et al.
Publicado: (2017)

Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker Investigations
por: Abdullah, Mardiaty Iryani, et al.
Publicado: (2019)

Tissue and serum samples of patients with papillary thyroid cancer with and without benign background demonstrate different altered expression of proteins
por: Abdullah, Mardiaty Iryani, et al.
Publicado: (2016)

Antioxidant-rich leaf extract of Barringtonia racemosa significantly alters the in vitro expression of genes encoding enzymes that are involved in methylglyoxal degradation III
por: Kong, Kin Weng, et al.
Publicado: (2016)

Functional Analyses of c.2268dup in Thyroid Peroxidase Gene Associated with Goitrous Congenital Hypothyroidism
por: Lee, Ching Chin, et al.
Publicado: (2014)

Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cells
por: Razali, Nurhanani, et al.
Publicado: (2015)

In Vivo Biochemical and Gene Expression Analyses of the Antioxidant Activities and Hypocholesterolaemic Properties of Tamarindus indica Fruit Pulp Extract
por: Lim, Chor Yin, et al.
Publicado: (2013)

Identification of a 3-Gene Prognostic Index for Papillary Thyroid Carcinoma
por: Zhong, Lin-Kun, et al.
Publicado: (2022)

Microarray analysis revealed different gene expression patterns in HepG2 cells treated with low and high concentrations of the extracts of Anacardium occidentale shoots
por: Khaleghi, Shaghayegh, et al.
Publicado: (2011)

Evaluation of Anti-proliferative Effects of Barringtonia racemosa and Gallic Acid on Caco-2 Cells
por: Ho, Ivan Y. M., et al.
Publicado: (2020)

Polyphenols from the extract and fraction of T. indica seeds protected HepG2 cells against oxidative stress
por: Razali, Nurhanani, et al.
Publicado: (2015)

Differentiated thyroid cancer in patients with resistance to thyroid hormone syndrome. A novel case and a review of the literature
por: Vinagre, João, et al.
Publicado: (2014)

Effects of Tamarindus indica Fruit Pulp Extract on Abundance of HepG2 Cell Lysate Proteins and Their Possible Consequential Impact on Metabolism and Inflammation
por: Chong, Ursula R. W., et al.
Publicado: (2013)

Function and Clinical Significance of Circular RNAs in Thyroid Cancer
por: Yao, Xuelin, et al.
Publicado: (2022)

Tamarindus indica Extract Alters Release of Alpha Enolase, Apolipoprotein A-I, Transthyretin and Rab GDP Dissociation Inhibitor Beta from HepG2 Cells
por: Chong, Ursula Rho Wan, et al.
Publicado: (2012)

Protective effects of the extracts of Barringtonia racemosa shoots against oxidative damage in HepG2 cells
por: Kong, Kin Weng, et al.
Publicado: (2016)

Lipidomic Perturbations in Cynomolgus Monkeys are Regulated by Thyroid Stimulating Hormone
por: Xu, Tao, et al.
Publicado: (2021)

Gene expression profiles in human HepG2 cells treated with extracts of the Tamarindus indica fruit pulp
por: Razali, Nurhanani, et al.
Publicado: (2010)

Characterization of the Immune Cell Infiltration Landscape of Thyroid Cancer for Improved Immunotherapy
por: Gong, Jing, et al.
Publicado: (2021)

Application of Proteomics in Pancreatic Ductal Adenocarcinoma Biomarker Investigations: A Review
por: Vellan, Christina Jane, et al.
Publicado: (2022)

A multifaceted assessment of strigolactone GR24 and its derivatives: from anticancer and antidiabetic activities to antioxidant capacity and beyond
por: Pyrzanowska-Banasiak, Agata, et al.
Publicado: (2023)

Modified Models for Predicting Malignancy Using Ultrasound Characters Have High Accuracy in Thyroid Nodules With Small Size
por: Jiang, Shan, et al.
Publicado: (2021)

Identification of immune-related ferroptosis prognostic marker and in-depth bioinformatics exploration of multi-omics mechanisms in thyroid cancer
por: Fan, Xin, et al.
Publicado: (2022)

Membrane Lipids in the Thyroid Comparing to Those in Non-Endocrine Tissues Are Less Sensitive to Pro-Oxidative Effects of Fenton Reaction Substrates
por: Stępniak, Jan, et al.
Publicado: (2022)

BSA-Stabilized Mesoporous Organosilica Nanoparticles Reversed Chemotherapy Resistance of Anaplastic Thyroid Cancer by Increasing Drug Uptake and Reducing Cellular Efflux
por: Han, Xiao, et al.
Publicado: (2020)

The Transcription-Repair Coupling Factor Mfd Prevents and Promotes Mutagenesis in a Context-Dependent Manner
por: Lindsey-Boltz, Laura A., et al.
Publicado: (2021)

A Novel, Homozygous c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian Sisters with Congenital Hypothyroidism and Multinodular Goiter
por: Lee, Ching Chin, et al.
Publicado: (2013)

Differential miRNA expression profiles in variants of papillary thyroid carcinoma and encapsulated follicular thyroid tumours
por: Sheu, S-Y, et al.
Publicado: (2010)

The molecular, immune features, and risk score construction of intraductal papillary mucinous neoplasm patients
por: Huang, Xing, et al.
Publicado: (2022)

Prevalence of c.2268dup and detection of two novel alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian–Chinese with thyroid dyshormonogenesis
por: Lee, Ching Chin, et al.
Publicado: (2015)

Cuproptosis patterns in papillary renal cell carcinoma are characterized by distinct tumor microenvironment infiltration landscapes
por: Zhang, Chiyu, et al.
Publicado: (2022)

Detection of human parvovirus B19 in papillary thyroid carcinoma
por: Wang, J H, et al.
Publicado: (2008)

Long non-coding RNA NBAT1, TUG1, miRNA-335, and miRNA-21 as potential biomarkers for acute ischemic stroke and their possible correlation to thyroid hormones
por: Mohammed, Asmaa, et al.
Publicado: (2022)

Comprehensive Analysis of Pyroptosis-Related Genes and Tumor Microenvironment Infiltration Characterization in Papillary Renal Cell Carcinoma
por: Zhang, Chiyu, et al.
Publicado: (2022)

Integrative Analysis of Immune-Related Genes in the Tumor Microenvironment of Renal Clear Cell Carcinoma and Renal Papillary Cell Carcinoma
por: Zheng, Bin, et al.
Publicado: (2021)

Comprehensive analysis of LAMC1 expression and prognostic value in kidney renal papillary cell carcinoma and clear cell carcinoma
por: Bai, Jianrong, et al.
Publicado: (2022)

Editorial: The repair of DNA–protein crosslinks
por: Sun, Yilun, et al.
Publicado: (2023)

Carbon Amendments Influence Composition and Functional Capacities of Indigenous Soil Microbiomes
por: Dundore-Arias, José Pablo, et al.
Publicado: (2020)

Thinking Outside the Frame: Impacting Genomes Capacity by Programmed Ribosomal Frameshifting
por: Riegger, Ricarda J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hmh7obeejvlrtqgfln7cnr1k1d