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YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice

Background: The inflammatory factor YKL-40 is associated with various inflammatory diseases and is key to remodeling inflammatory cells and tissues. YKL-40 (Chi3l1) promotes the activation of tissue factor (TF), leading to intrahepatic vascular coagulation (IAOC) and liver injury. TF is a key promot...

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Detalles Bibliográficos
Autores principales: Jing-Lun, Zhan, Shuang, Chai, Li-Mei, Zhao, Xiao-Dong, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484592/
https://www.ncbi.nlm.nih.gov/pubmed/37693903
http://dx.doi.org/10.3389/fphar.2023.1205062