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SARS-CoV-2 NSP1 induces mRNA cleavages on the ribosome

In severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the non-structural protein NSP1 inhibits translation of host mRNAs by binding to the mRNA entry channel of the ribosome and, together with the 5′-untranslated region (UTR) of the viral mRNAs, allows the evasion of that inhibition. Here...

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Detalles Bibliográficos
Autores principales: Tardivat, Yann, Sosnowski, Piotr, Tidu, Antonin, Westhof, Eric, Eriani, Gilbert, Martin, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484668/
https://www.ncbi.nlm.nih.gov/pubmed/37503833
http://dx.doi.org/10.1093/nar/gkad627