Enhanced frequency of transcription pre-initiation complexes assembly after exposure to UV irradiation results in increased repair activity and reduced probabilities for mutagenesis

In addition to being essential for gene expression, transcription is crucial for the maintenance of genome integrity. Here, we undertook a systematic approach, to monitor the assembly kinetics of the pre-initiating RNA Polymerase (Pol) II at promoters at steady state and different stages during reco...

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Detalles Bibliográficos
Autores principales: Liakos, Anastasios, Synacheri, Anna-Chloe, Konstantopoulos, Dimitris, Stefos, Georgios C, Lavigne, Matthieu D, Fousteri, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484669/
https://www.ncbi.nlm.nih.gov/pubmed/37470822
http://dx.doi.org/10.1093/nar/gkad593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484669/
https://www.ncbi.nlm.nih.gov/pubmed/37470822
http://dx.doi.org/10.1093/nar/gkad593

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