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IGHV allele similarity clustering improves genotype inference from adaptive immune receptor repertoire sequencing data

In adaptive immune receptor repertoire analysis, determining the germline variable (V) allele associated with each T- and B-cell receptor sequence is a crucial step. This process is highly impacted by allele annotations. Aligning sequences, assigning them to specific germline alleles, and inferring...

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Detalles Bibliográficos
Autores principales: Peres, Ayelet, Lees, William D, Rodriguez, Oscar L, Lee, Noah Y, Polak, Pazit, Hope, Ronen, Kedmi, Meirav, Collins, Andrew M, Ohlin, Mats, Kleinstein, Steven H, Watson, Corey T, Yaari, Gur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484671/
https://www.ncbi.nlm.nih.gov/pubmed/37548401
http://dx.doi.org/10.1093/nar/gkad603