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NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells

NAT10-catalyzed N(4)-acetylcytidine (ac(4)C) has emerged as a vital post-transcriptional modulator on the coding transcriptome by promoting mRNA stability. However, its role in mammalian development remains unclear. Here, we found that NAT10 expression positively correlates with pluripotency in vivo...

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Detalles Bibliográficos
Autores principales:	Liu, Rucong, Wubulikasimu, Zibaguli, Cai, Runze, Meng, Fanyi, Cui, Qinghua, Zhou, Yuan, Li, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484679/ https://www.ncbi.nlm.nih.gov/pubmed/37497776 http://dx.doi.org/10.1093/nar/gkad628

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