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Structures of CTCF–DNA complexes including all 11 zinc fingers

The CCCTC-binding factor (CTCF) binds tens of thousands of enhancers and promoters on mammalian chromosomes by means of its 11 tandem zinc finger (ZF) DNA-binding domain. In addition to the 12–15-bp CORE sequence, some of the CTCF binding sites contain 5′ upstream and/or 3′ downstream motifs. Here,...

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Detalles Bibliográficos
Autores principales:	Yang, Jie, Horton, John R, Liu, Bin, Corces, Victor G, Blumenthal, Robert M, Zhang, Xing, Cheng, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484683/ https://www.ncbi.nlm.nih.gov/pubmed/37439339 http://dx.doi.org/10.1093/nar/gkad594

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