Genome-wide mapping of i-motifs reveals their association with transcription regulation in live human cells

i-Motifs (iMs) are four-stranded DNA structures that form at cytosine (C)-rich sequences in acidic conditions in vitro. Their formation in cells is still under debate. We performed CUT&Tag sequencing using the anti-iM antibody iMab and showed that iMs form within the human genome in live cells....

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Detalles Bibliográficos
Autores principales: Zanin, Irene, Ruggiero, Emanuela, Nicoletto, Giulia, Lago, Sara, Maurizio, Ilaria, Gallina, Irene, Richter, Sara N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484731/
https://www.ncbi.nlm.nih.gov/pubmed/37528048
http://dx.doi.org/10.1093/nar/gkad626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484731/
https://www.ncbi.nlm.nih.gov/pubmed/37528048
http://dx.doi.org/10.1093/nar/gkad626

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