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Surveillance of 3′ mRNA cleavage during transcription termination requires CF IB/Hrp1

CF IB/Hrp1 is part of the cleavage and polyadenylation factor (CPF) and cleavage factor (CF) complex (CPF–CF), which is responsible for 3′ cleavage and maturation of pre-mRNAs. Although Hrp1 supports this process, its presence is not essential for the cleavage event. Here, we show that the main func...

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Detalles Bibliográficos
Autores principales: Li, Jing, Querl, Luisa, Coban, Ivo, Salinas, Gabriela, Krebber, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484732/
https://www.ncbi.nlm.nih.gov/pubmed/37351636
http://dx.doi.org/10.1093/nar/gkad530