Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA

Transcription factors, such as nuclear receptors achieve precise transcriptional regulation by means of a tight and reciprocal communication with DNA, where cooperativity gained by receptor dimerization is added to binding site sequence specificity to expand the range of DNA target gene sequences. T...

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Detalles Bibliográficos
Autores principales: Patel, Abdul Kareem Mohideen, Vilela, Pierre, Shaik, Tajith Baba, McEwen, Alastair G, Hazemann, Isabelle, Brillet, Karl, Ennifar, Eric, Hamiche, Ali, Markov, Gabriel V, Laudet, Vincent, Moras, Dino, Klaholz, Bruno P, Billas, Isabelle M L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484738/
https://www.ncbi.nlm.nih.gov/pubmed/37503845
http://dx.doi.org/10.1093/nar/gkad632

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