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Somatic mutations in facial skin from countries of contrasting skin cancer risk

The incidence of keratinocyte cancer (basal cell and squamous cell carcinomas of the skin) is 17-fold lower in Singapore than the UK(1–3), despite Singapore receiving 2–3 times more ultraviolet (UV) radiation(4,5). Aging skin contains somatic mutant clones from which such cancers develop(6,7). We hy...

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Detalles Bibliográficos
Autores principales: King, Charlotte, Fowler, Joanna C., Abnizova, Irina, Sood, Roshan K., Hall, Michael W. J., Szeverényi, Ildikó, Tham, Muly, Huang, Jingxiang, Young, Stephanie Ming, Hall, Benjamin A., Birgitte Lane, E., Jones, Philip H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484783/
https://www.ncbi.nlm.nih.gov/pubmed/37537257
http://dx.doi.org/10.1038/s41588-023-01468-x