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Background and roles: myosin in autoimmune diseases
The myosin superfamily is a group of molecular motors. Autoimmune diseases are characterized by dysregulation or deficiency of the immune tolerance mechanism, resulting in an immune response to the human body itself. The link between myosin and autoimmune diseases is much more complex than scientist...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484797/ https://www.ncbi.nlm.nih.gov/pubmed/37691828 http://dx.doi.org/10.3389/fcell.2023.1220672 |
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author | Fu, Longsheng Zou, Yonghui Yu, Boyang Hong, Daojun Guan, Teng Hu, Jinfang Xu, Yi Wu, Yaoqi Kou, Junping Lv, Yanni |
author_facet | Fu, Longsheng Zou, Yonghui Yu, Boyang Hong, Daojun Guan, Teng Hu, Jinfang Xu, Yi Wu, Yaoqi Kou, Junping Lv, Yanni |
author_sort | Fu, Longsheng |
collection | PubMed |
description | The myosin superfamily is a group of molecular motors. Autoimmune diseases are characterized by dysregulation or deficiency of the immune tolerance mechanism, resulting in an immune response to the human body itself. The link between myosin and autoimmune diseases is much more complex than scientists had hoped. Myosin itself immunization can induce experimental autoimmune diseases of animals, and myosins were abnormally expressed in a number of autoimmune diseases. Additionally, myosin takes part in the pathological process of multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, autoimmune myocarditis, myositis, hemopathy, inclusion body diseases, etc. However, research on myosin and its involvement in the occurrence and development of diseases is still in its infancy, and the underlying pathological mechanisms are not well understood. We can reasonably predict that myosin might play a role in new treatments of autoimmune diseases. |
format | Online Article Text |
id | pubmed-10484797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104847972023-09-09 Background and roles: myosin in autoimmune diseases Fu, Longsheng Zou, Yonghui Yu, Boyang Hong, Daojun Guan, Teng Hu, Jinfang Xu, Yi Wu, Yaoqi Kou, Junping Lv, Yanni Front Cell Dev Biol Cell and Developmental Biology The myosin superfamily is a group of molecular motors. Autoimmune diseases are characterized by dysregulation or deficiency of the immune tolerance mechanism, resulting in an immune response to the human body itself. The link between myosin and autoimmune diseases is much more complex than scientists had hoped. Myosin itself immunization can induce experimental autoimmune diseases of animals, and myosins were abnormally expressed in a number of autoimmune diseases. Additionally, myosin takes part in the pathological process of multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, autoimmune myocarditis, myositis, hemopathy, inclusion body diseases, etc. However, research on myosin and its involvement in the occurrence and development of diseases is still in its infancy, and the underlying pathological mechanisms are not well understood. We can reasonably predict that myosin might play a role in new treatments of autoimmune diseases. Frontiers Media S.A. 2023-08-23 /pmc/articles/PMC10484797/ /pubmed/37691828 http://dx.doi.org/10.3389/fcell.2023.1220672 Text en Copyright © 2023 Fu, Zou, Yu, Hong, Guan, Hu, Xu, Wu, Kou and Lv. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cell and Developmental Biology Fu, Longsheng Zou, Yonghui Yu, Boyang Hong, Daojun Guan, Teng Hu, Jinfang Xu, Yi Wu, Yaoqi Kou, Junping Lv, Yanni Background and roles: myosin in autoimmune diseases |
title | Background and roles: myosin in autoimmune diseases |
title_full | Background and roles: myosin in autoimmune diseases |
title_fullStr | Background and roles: myosin in autoimmune diseases |
title_full_unstemmed | Background and roles: myosin in autoimmune diseases |
title_short | Background and roles: myosin in autoimmune diseases |
title_sort | background and roles: myosin in autoimmune diseases |
topic | Cell and Developmental Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484797/ https://www.ncbi.nlm.nih.gov/pubmed/37691828 http://dx.doi.org/10.3389/fcell.2023.1220672 |
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