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Collaborative impact of bacterial exometabolites governing root microbiota formation
The majority of the root microbiota formation derives from soil-dwelling microorganisms. The limited extent of thorough investigation leads to a dearth of knowledge concerning the intricate mechanisms of microbe-microbe interaction implicated in the establishment of root microbiota. Therefore, the t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484853/ https://www.ncbi.nlm.nih.gov/pubmed/37676462 http://dx.doi.org/10.1007/s44154-023-00121-1 |
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author | Kareem, Hafiz Abdul Hao, Xinwei Shen, Xihui |
author_facet | Kareem, Hafiz Abdul Hao, Xinwei Shen, Xihui |
author_sort | Kareem, Hafiz Abdul |
collection | PubMed |
description | The majority of the root microbiota formation derives from soil-dwelling microorganisms. The limited extent of thorough investigation leads to a dearth of knowledge concerning the intricate mechanisms of microbe-microbe interaction implicated in the establishment of root microbiota. Therefore, the taxonomic signatures in bacterial inhibition profiles were determined by in vitro testing of 39,204 binary interbacterial interactions. However, findings from genetic and metabolomic studies elucidated that co-functioning of the antimicrobial 2,4-d iacetylphloroglucinol (DAPG) and the iron chelator pyoverdine as exometabolites has significantly contributed to the potent inhibitory activities of the highly antagonistic Pseudomonas brassicacearum R401. Microbiota restoration with a core of Arabidopsis thaliana root commensals showed that these exometabolites possess a root niche-specific function in establishing root competence and inducing anticipated changes in root surroundings. Both biosynthetic operons are abundant in roots in natural habitats, indicating that these exometabolites co-functioning is an adaptive feature that helps Pseudomonad dominate the root microbiota. |
format | Online Article Text |
id | pubmed-10484853 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Nature Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-104848532023-09-09 Collaborative impact of bacterial exometabolites governing root microbiota formation Kareem, Hafiz Abdul Hao, Xinwei Shen, Xihui Stress Biol Highlights The majority of the root microbiota formation derives from soil-dwelling microorganisms. The limited extent of thorough investigation leads to a dearth of knowledge concerning the intricate mechanisms of microbe-microbe interaction implicated in the establishment of root microbiota. Therefore, the taxonomic signatures in bacterial inhibition profiles were determined by in vitro testing of 39,204 binary interbacterial interactions. However, findings from genetic and metabolomic studies elucidated that co-functioning of the antimicrobial 2,4-d iacetylphloroglucinol (DAPG) and the iron chelator pyoverdine as exometabolites has significantly contributed to the potent inhibitory activities of the highly antagonistic Pseudomonas brassicacearum R401. Microbiota restoration with a core of Arabidopsis thaliana root commensals showed that these exometabolites possess a root niche-specific function in establishing root competence and inducing anticipated changes in root surroundings. Both biosynthetic operons are abundant in roots in natural habitats, indicating that these exometabolites co-functioning is an adaptive feature that helps Pseudomonad dominate the root microbiota. Springer Nature Singapore 2023-09-07 /pmc/articles/PMC10484853/ /pubmed/37676462 http://dx.doi.org/10.1007/s44154-023-00121-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Highlights Kareem, Hafiz Abdul Hao, Xinwei Shen, Xihui Collaborative impact of bacterial exometabolites governing root microbiota formation |
title | Collaborative impact of bacterial exometabolites governing root microbiota formation |
title_full | Collaborative impact of bacterial exometabolites governing root microbiota formation |
title_fullStr | Collaborative impact of bacterial exometabolites governing root microbiota formation |
title_full_unstemmed | Collaborative impact of bacterial exometabolites governing root microbiota formation |
title_short | Collaborative impact of bacterial exometabolites governing root microbiota formation |
title_sort | collaborative impact of bacterial exometabolites governing root microbiota formation |
topic | Highlights |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484853/ https://www.ncbi.nlm.nih.gov/pubmed/37676462 http://dx.doi.org/10.1007/s44154-023-00121-1 |
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