Integrative blood-based characterization of oxidative mitochondrial DNA damage variants implicates Mexican American’s metabolic risk for developing Alzheimer’s disease

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Alzheimer’s Disease (AD) continues to be a leading cause of death in the US. As the US aging population (ages 65 +) expands, the impact will disproportionately affect vulnerable populations, e.g., Hispanic/Latino population, due to their AD-related health disparities. Age-related regression in mitoc...

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Detalles Bibliográficos
Autores principales: Reid, Danielle Marie, Barber, Robert C., Jones, Harlan P., Thorpe, Roland J., Sun, Jie, Zhou, Zhengyang, Phillips, Nicole R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484983/
https://www.ncbi.nlm.nih.gov/pubmed/37679478
http://dx.doi.org/10.1038/s41598-023-41190-6
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