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USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target
An essential protein regulatory system in cells is the ubiquitin-proteasome pathway. The substrate is modified by the ubiquitin ligase system (E1-E2-E3) in this pathway, which is a dynamic protein bidirectional modification regulation system. Deubiquitinating enzymes (DUBs) are tasked with specifica...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485055/ https://www.ncbi.nlm.nih.gov/pubmed/37679322 http://dx.doi.org/10.1038/s41420-023-01629-1 |