USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target

An essential protein regulatory system in cells is the ubiquitin-proteasome pathway. The substrate is modified by the ubiquitin ligase system (E1-E2-E3) in this pathway, which is a dynamic protein bidirectional modification regulation system. Deubiquitinating enzymes (DUBs) are tasked with specifica...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Song, Yang, Wang, Kexin, Liu, Guoxiang, Dong, Xiaolei, Yang, Fanghao, Chen, Guang, Cao, Can, Zhang, Huhu, Wang, Mengjun, Li, Ya, Zeng, Teng, Liu, Chunyan, Li, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485055/
https://www.ncbi.nlm.nih.gov/pubmed/37679322
http://dx.doi.org/10.1038/s41420-023-01629-1

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