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Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-β-cyclodextrin column using polar organic mode

The chiral separation capability of Chiral-CD-Ph column, containing phenylcarbamate-β-cyclodextrin as the chiral selector in polar organic mode was investigated. A total of twenty-five compounds with different structures and acid–base properties were evaluated, and twenty of them were separated usin...

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Detalles Bibliográficos
Autores principales: Dobó, Máté, Ádám, Márk, Fiser, Béla, Papp, Lajos Attila, Dombi, Gergely, Sekkoum, Khaled, Szabó, Zoltán-István, Tóth, Gergő
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485059/
https://www.ncbi.nlm.nih.gov/pubmed/37679395
http://dx.doi.org/10.1038/s41598-023-41941-5

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