PCSK9 Inhibition Reduces Depressive like Behavior in CUMS-Exposed Rats: Highlights on HMGB1/RAGE/TLR4 Pathway, NLRP3 Inflammasome Complex and IDO-1

Ample evidence has pointed to a close link between cardiovascular diseases (CVD) and depression. Inflammatory pathways including the high-mobility-group-box-1 protein, receptor-for-advanced-glycation-end-products and toll-like-receptor-4 (HMGB1/RAGE/TLR4) and nucleotide-binding domain (NOD)–like rec...

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Detalles Bibliográficos
Autores principales: Hendawy, Nevien, Salaheldin, Tala H., Abuelezz, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485135/
https://www.ncbi.nlm.nih.gov/pubmed/36781714
http://dx.doi.org/10.1007/s11481-023-10060-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485135/
https://www.ncbi.nlm.nih.gov/pubmed/36781714
http://dx.doi.org/10.1007/s11481-023-10060-3

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