Biochemical functions and structure of Caenorhabditis elegans ZK177.8 protein: Aicardi–Goutières syndrome SAMHD1 dNTPase ortholog

Mutations in sterile alpha motif domain and histidine–aspartate domain–containing protein 1 (SAMHD1) are found in a neurodevelopmental disorder, Aicardi–Goutières syndrome, and cancers, and SAMHD1, which is a deoxynucleoside triphosphate (dNTP) triphosphorylase, was identified as a myeloid-specific...

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Detalles Bibliográficos
Autores principales: Maehigashi, Tatsuya, Lim, Christopher, Wade, Lydia R., Bowen, Nicole E., Knecht, Kirsten M., Alvarez, Natalie N., Kelly, William G., Schinazi, Raymond F., Kim, Dong-Hyun, Xiong, Yong, Kim, Baek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485159/
https://www.ncbi.nlm.nih.gov/pubmed/37567474
http://dx.doi.org/10.1016/j.jbc.2023.105148

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