Mycobacterium tuberculosis impairs human memory CD4(+) T cell recognition of M2 but not M1-like macrophages

Direct recognition of Mycobacterium tuberculosis (Mtb)-infected cells is required for protection by CD4(+) T cells. While impaired T cell recognition of Mtb-infected macrophages was demonstrated in mice, data are lacking for humans. Using T cells and monocyte-derived macrophages (MDMs) from individu...

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Detalles Bibliográficos
Autores principales: Gail, Daniel P., Suzart, Vinicius G., Du, Weinan, Kaur Sandhu, Avinaash, Jarvela, Jessica, Nantongo, Mary, Mwebaza, Ivan, Panigrahi, Soumya, Freeman, Michael L., Canaday, David H., Boom, W. Henry, Silver, Richard F., Carpenter, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485162/
https://www.ncbi.nlm.nih.gov/pubmed/37694142
http://dx.doi.org/10.1016/j.isci.2023.107706

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