METTL3‐mediated m(6)A modification of circPRKAR1B promotes Crohn's colitis by inducing pyroptosis via autophagy inhibition

BACKGROUND: The roles of circRNA and N6‐methyladenosine (m(6)A) methylation in Crohn's disease (CD) have drawn much attention. Therefore, this investigation aimed to discover how the m(6)A modification of circRNAs contributes to CD progression. METHODS: The study performed circRNA sequencing on...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Zhao, Zhibin, Ying, Pu, Zhou, Yan, Xu, Ziwei, Wang, Honggang, Tang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485333/
https://www.ncbi.nlm.nih.gov/pubmed/37679886
http://dx.doi.org/10.1002/ctm2.1405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485333/
https://www.ncbi.nlm.nih.gov/pubmed/37679886
http://dx.doi.org/10.1002/ctm2.1405

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