Ventilator support in the pretransplant period predisposes early graft failure after deceased donor liver transplantation

PURPOSE: Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified. METHODS: From August 2017 to February 2021, 265 adult DDLTs were...

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Detalles Bibliográficos
Autores principales: Lee, Nuri, Cha, Sora, Kim, Jongman, Lee, Yunmi, Kang, Enjin, Kim, Hyun Jung, Hong, Seung Hui, Rhu, Jinsoo, Choi, Gyu-Seong, Joh, Jae-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Surgical Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485352/
https://www.ncbi.nlm.nih.gov/pubmed/37693286
http://dx.doi.org/10.4174/astr.2023.105.3.141
Descripción
Sumario:PURPOSE: Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified. METHODS: From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with and without 30-day graft failure were compared. RESULTS: Liver graft failure occurred in 11 patients (17.7%) after DDLT. Baseline and perioperative characteristics of donors and recipients were not statistically significantly different between the 2 groups. The cumulative graft and overall survival rates at 6 months were 83.9% and 88.7%, respectively. Multivariate analysis showed ventilator support in the pretransplant period was a predisposing factor for 30-day graft failure after DDLT. CONCLUSION: Present study indicates that cautious decision is required when allocating DDLT in critically ill patients on mechanical ventilatory support.

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