Cargando…

The m(6)A-related gene signature stratifies poor prognosis patients and characterizes immunosuppressive microenvironment in hepatocellular carcinoma

BACKGROUND: N(6)-methyladenosine (m(6)A) is the most abundant epitranscriptomic modification of RNA, which can affect RNA metabolism and protein translation. The m(6)A modification plays a critical role in cancer development, including hepatocellular carcinoma (HCC). Despite several m(6)A-related si...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Ensi, Li, Jianhua, Shen, Conghuan, Gu, Yange, Zhang, Xinju, Li, Li, Zhao, Jing, Wang, Zhengxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485364/ https://www.ncbi.nlm.nih.gov/pubmed/37691948 http://dx.doi.org/10.3389/fimmu.2023.1227593

Ejemplares similares

Prognosis and Dissection of Immunosuppressive Microenvironment in Breast Cancer Based on Fatty Acid Metabolism-Related Signature
por: Tang, Yuhui, et al.
Publicado: (2022)

Development of a predictive nomogram for early recurrence of hepatocellular carcinoma in patients undergoing liver transplantation
por: Ma, Ensi, et al.
Publicado: (2021)

Hypoxic Characteristic in the Immunosuppressive Microenvironment of Hepatocellular Carcinoma
por: Mo, Zhuomao, et al.
Publicado: (2021)

Overexpression of SMS in the tumor microenvironment is associated with immunosuppression in hepatocellular carcinoma
por: Xiang, Lin, et al.
Publicado: (2022)

Prognosis stratification in breast cancer and characterization of immunosuppressive microenvironment through a pyrimidine metabolism-related signature
por: Luo, Yongzhou, et al.
Publicado: (2022)

TANK shapes an immunosuppressive microenvironment and predicts prognosis and therapeutic response in glioma
por: Li, Shasha, et al.
Publicado: (2023)

PKM2 Drives Hepatocellular Carcinoma Progression by Inducing Immunosuppressive Microenvironment
por: Li, Tian-En, et al.
Publicado: (2020)

Prognosis and Tumour Immune Microenvironment of Patients With Hepatocellular Carcinoma by a Novel Pyroptosis-Related lncRNA Signature
por: Zhang, Ze, et al.
Publicado: (2022)

Obesity contributes to hepatocellular carcinoma development via immunosuppressive microenvironment remodeling
por: Yang, Jian, et al.
Publicado: (2023)

Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma
por: Chen, Quan, et al.
Publicado: (2023)

Apoptosis, Pyroptosis, and Ferroptosis Conspiringly Induce Immunosuppressive Hepatocellular Carcinoma Microenvironment and γδ T-Cell Imbalance
por: Hu, Yi, et al.
Publicado: (2022)

Itaconic acid facilitates inflammation abatement and alleviates liver ischemia-reperfusion injury by inhibiting NF-κB/NLRP3/caspase-1 inflammasome axis
por: Ma, Ensi, et al.
Publicado: (2022)

Comprehensive analysis of the amino acid metabolism-related gene signature for prognosis, tumor immune microenvironment, and candidate drugs in hepatocellular carcinoma
por: Li, Yue, et al.
Publicado: (2022)

Identifying the EMT-related signature to stratify prognosis and evaluate the tumor microenvironment in lung adenocarcinoma
por: Li, Feng, et al.
Publicado: (2022)

Effects of Tumor-Derived DNA on CXCL12-CXCR4 and CCL21-CCR7 Axes of Hepatocellular Carcinoma Cells and the Regulation of Sinomenine Hydrochloride
por: Shen, Conghuan, et al.
Publicado: (2022)

High serum soluble CD155 level predicts poor prognosis and correlates with an immunosuppressive tumor microenvironment in hepatocellular carcinoma
por: Jin, An‐Li, et al.
Publicado: (2022)

SENP1 is a crucial promotor for hepatocellular carcinoma through deSUMOylation of UBE2T
por: Tao, Yifeng, et al.
Publicado: (2020)

An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment
por: Abou Khouzam, Raefa, et al.
Publicado: (2021)

The m6A/m5C/m1A Regulated Gene Signature Predicts the Prognosis and Correlates With the Immune Status of Hepatocellular Carcinoma
por: Li, Dan, et al.
Publicado: (2022)

Axl Expression Stratifies Patients with Poor Prognosis after Hepatectomy for Hepatocellular Carcinoma
por: Liu, Jian, et al.
Publicado: (2016)

Single-cell RNA sequencing highlights the role of PVR/PVRL2 in the immunosuppressive tumour microenvironment in hepatocellular carcinoma
por: Li, Ang, et al.
Publicado: (2023)

PROS1 shapes the immune-suppressive tumor microenvironment and predicts poor prognosis in glioma
por: Wang, Jinxiang, et al.
Publicado: (2023)

Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma
por: DeCordova, Syreeta, et al.
Publicado: (2020)

The immunosuppressive microenvironment and immunotherapy in human glioblastoma
por: Zhang, Xuehua, et al.
Publicado: (2022)

Intratumoral CD73: An immune checkpoint shaping an inhibitory tumor microenvironment and implicating poor prognosis in Chinese melanoma cohorts
por: Gao, Zixu, et al.
Publicado: (2022)

The signature of cuproptosis-related immune genes predicts the tumor microenvironment and prognosis of prostate adenocarcinoma
por: Yao, Kai, et al.
Publicado: (2023)

The Hypoxic Landscape Stratifies Gastric Cancer Into 3 Subtypes With Distinct M6a Methylation and Tumor Microenvironment Infiltration Characteristics
por: Ning, Zhi-kun, et al.
Publicado: (2022)

CCND1 Amplification Profiling Identifies a Subtype of Melanoma Associated With Poor Survival and an Immunosuppressive Tumor Microenvironment
por: Liu, Jun, et al.
Publicado: (2022)

CCND1 Amplification Contributes to Immunosuppression and Is Associated With a Poor Prognosis to Immune Checkpoint Inhibitors in Solid Tumors
por: Chen, Yu, et al.
Publicado: (2020)

A Novel m1A-Score Model Correlated With the Immune Microenvironment Predicts Prognosis in Hepatocellular Carcinoma
por: Zhao, Mingxing, et al.
Publicado: (2022)

Deciphering a mitochondria-related signature to supervise prognosis and immunotherapy in hepatocellular carcinoma
por: Shi, Yanlong, et al.
Publicado: (2022)

Lipid metabolism-related gene signature predicts prognosis and depicts tumor microenvironment immune landscape in gliomas
por: Li, Junhong, et al.
Publicado: (2023)

Identification of a CD4+ conventional T cells-related lncRNAs signature associated with hepatocellular carcinoma prognosis, therapy, and tumor microenvironment
por: Zhu, Lin, et al.
Publicado: (2023)

Cancer Stem Cells and Immunosuppressive Microenvironment in Glioma
por: Ma, Qianquan, et al.
Publicado: (2018)

The pyroptosis-related gene signature predicts prognosis and indicates the immune microenvironment status of chronic lymphocytic leukemia
por: Sha, Yeqin, et al.
Publicado: (2022)

The cancer-associated fibroblast-related signature predicts prognosis and indicates immune microenvironment infiltration in gastric cancer
por: Mak, Tsz Kin, et al.
Publicado: (2022)

ALOX5AP Predicts Poor Prognosis by Enhancing M2 Macrophages Polarization and Immunosuppression in Serous Ovarian Cancer Microenvironment
por: Ye, Xiang, et al.
Publicado: (2021)

Identifying a baicalein-related prognostic signature contributes to prognosis prediction and tumor microenvironment of pancreatic cancer
por: Zhang, Citing, et al.
Publicado: (2023)

Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy
por: Li, Yiliang, et al.
Publicado: (2018)

Genetic Changes Driving Immunosuppressive Microenvironments in Oral Premalignancy
por: Rangel, Roberto, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_khkgh8so834am7nes06np4bulu