Cargando…

Clinical, molecular, and immune correlates of the Immunotherapy Response Score in patients with advanced urothelial carcinoma under atezolizumab monotherapy: analysis of the phase II IMvigor210 trial

BACKGROUND: In the advanced urothelial carcinoma (aUC) scenario there are no consistent immune checkpoint blockade predictive biomarkers. Recently a novel pan-tumor molecular tissue-based biomarker, the Immunotherapy Response Score (IRS), has been proposed. We conducted a retrospective study to vali...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferreiro-Pantín, M., Anido-Herranz, U., Betancor, Y.Z., Cebey-López, V., León-Mateos, L., García-González, J., García-Acuña, S.M., Fernández-Díaz, N., Tubio, J.M.C., López-López, R., Ruiz-Bañobre, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485401/ https://www.ncbi.nlm.nih.gov/pubmed/37516059 http://dx.doi.org/10.1016/j.esmoop.2023.101611

Ejemplares similares

Atezolizumab in locally advanced or metastatic urothelial cancer: a pooled analysis from the Spanish patients of the IMvigor 210 cohort 2 and 211 studies
por: Sotelo, M., et al.
Publicado: (2020)

Role of atezolizumab therapy combined with platinum-based chemotherapy in untreated metastatic urothelial carcinoma – The new landscapes (IMvigor130 trial)
por: Misra, Ankit
Publicado: (2021)

Rethinking prognostic factors in locally advanced or metastatic urothelial carcinoma in the immune checkpoint blockade era: a multicenter retrospective study
por: Ruiz-Bañobre, J., et al.
Publicado: (2021)

Long-term Response to Nivolumab and Acute Renal Failure in a Patient with Metastatic Papillary Renal Cell Carcinoma and a PD-L1 Tumor Expression Increased with Sunitinib Therapy: A Case Report
por: Ruiz-Bañobre, Juan, et al.
Publicado: (2016)

MSIMEP: Predicting microsatellite instability from microarray DNA methylation tumor profiles
por: Santamarina-García, Martín, et al.
Publicado: (2023)

Phase II multicohort study of atezolizumab monotherapy in multiple advanced solid cancers
por: Tabernero, J., et al.
Publicado: (2022)

Ascites-Derived Organoids to Depict Platinum Resistance in Gynaecological Serous Carcinomas
por: Arias-Diaz, Andrea Estrella, et al.
Publicado: (2023)

Clinical significance of baseline Pan-Immune-Inflammation Value and its dynamics in metastatic colorectal cancer patients under first-line chemotherapy
por: Pérez-Martelo, Martín, et al.
Publicado: (2022)

Longitudinal CTCs gene expression analysis on metastatic castration-resistant prostate cancer patients treated with docetaxel reveals new potential prognosis markers
por: Pereira-Veiga, Thais, et al.
Publicado: (2021)

Significance of inflammatory indexes in atezolizumab monotherapy outcomes in previously treated non-small-cell lung cancer patients
por: Katayama, Yuki, et al.
Publicado: (2020)

(226)Ra, (210)Pb, (210)Bi and (210)Po deposition and removal from surfaces and liquids
por: Wójcik, M., et al.
Publicado: (2012)

Clinical Application of Circulating Tumour Cells in Prostate Cancer: From Bench to Bedside and Back
por: León-Mateos, Luis, et al.
Publicado: (2016)

Use of multikinase inhibitors/lenvatinib concomitant with radioiodine for the treatment of radioiodine refractory differentiated thyroid cancer
por: Herranz, Urbano Anido
Publicado: (2022)

Efficacy and safety of amrubicin monotherapy after atezolizumab plus carboplatin and etoposide in patients with relapsed small-cell lung cancer
por: Imai, Hisao, et al.
Publicado: (2022)

The Glasgow Prognostic Score Predicts Outcomes of Pembrolizumab or Atezolizumab Monotherapy in Patients with Pretreated Non-Small Cell Lung Cancer
por: Kasajima, Masashi, et al.
Publicado: (2023)

Recognising the asymptomatic enemy
por: Cebey-López, Miriam, et al.
Publicado: (2021)

The decay of $^{210}_{86}$Rn$_{124}$ to levels in $^{210}_{85}$At$_{125}$
por: Jonson, B, et al.
Publicado: (1972)

Evaluation of Novel Doxorubicin-Loaded Magnetic Wax Nanocomposite Vehicles as Cancer Combinatorial Therapy Agents
por: Jiménez-López, Julia, et al.
Publicado: (2020)

Solid Lipid Particles for Lung Metastasis Treatment
por: Valdivia, Lourdes, et al.
Publicado: (2021)

Atezolizumab Monotherapy or Plus Chemotherapy in First-Line Treatment for Advanced Non-Small Cell Lung Cancer Patients: A Meta-Analysis
por: Li, Dan-Ni, et al.
Publicado: (2021)

A sensitive method to determine (210)Po and (210)Pb in environmental samples by alpha spectrometry using CuS micro-precipitation
por: Walsh, Stephanie, et al.
Publicado: (2023)

Memorandum: membership of the Collaboration, experiment R210
por: Becker, U, et al.
Publicado: (1980)

Grade Retention in Primary Education Is Associated with Quarter of Birth and Socioeconomic Status
por: González-Betancor, Sara M., et al.
Publicado: (2016)

The nucleoporin gp210/Nup210 controls muscle differentiation by regulating nuclear envelope/ER homeostasis
por: Gomez-Cavazos, J. Sebastian, et al.
Publicado: (2015)

Antibiofilm Efficacy of the Pseudomonas aeruginosa Pbunavirus vB_PaeM-SMS29 Loaded onto Dissolving Polyvinyl Alcohol Microneedles
por: Sillankorva, Sanna, et al.
Publicado: (2022)

The antihydrogen discovery: PS210 Collaboration
por: Macri, M
Publicado: (1996)

Unusual Case of Superior Vena Cava Syndrome Caused by Intravascular Thyroid Metastasis
por: Varela Pose, Vanesa, et al.
Publicado: (2017)

Discrete-Event Simulation Thermal Model for Extrusion-Based Additive Manufacturing of PLA and ABS
por: Bhandari, Sunil, et al.
Publicado: (2020)

Transition probabilities of low-lying excited states in 210Po and 210Pb
por: Georgiev, Georgi, et al.
Publicado: (2022)

Determination of the mean aerosol residence times in the atmosphere and additional (210)Po input on the base of simultaneous determination of (7)Be, (22)Na, (210)Pb, (210)Bi and (210)Po in urban air
por: Długosz-Lisiecka, Magdalena, et al.
Publicado: (2012)

Atezolizumab plus bevacizumab versus sorafenib or atezolizumab alone for unresectable hepatocellular carcinoma: A systematic review
por: Ahmed, Faiza, et al.
Publicado: (2021)

Radionuclides ((210)Po and (210)Pb) and Some Heavy Metals in Fish and Sediments in Lake Bafa, Turkey, and the Contribution of (210)Po to the Radiation Dose
por: Manav, Ramazan, et al.
Publicado: (2016)

Atmospheric fallout impact on (210)Po and (210)Pb content in wild growing mushrooms
por: Szymańska, Karolina, et al.
Publicado: (2020)

Sources of Polonium (210)Po and Radio-Lead (210)Pb in Human Body in Poland
por: Boryło, Alicja, et al.
Publicado: (2022)

Daptomycin plus fosfomycin versus daptomycin monotherapy in treating MRSA: protocol of a multicentre, randomised, phase III trial
por: Shaw, E, et al.
Publicado: (2015)

Developments in Pb-210 methodologies to provide chronologies for environmental change
por: Hunter, H. N., et al.
Publicado: (2022)

Effectiveness of Pregabalin as Monotherapy or Combination Therapy for Neuropathic Pain in Patients Unresponsive to Previous Treatments in a Spanish Primary Care Setting
por: Blanco Tarrio, Emilio, et al.
Publicado: (2013)

Phase I dose-finding study of monotherapy with atezolizumab, an engineered immunoglobulin monoclonal antibody targeting PD-L1, in Japanese patients with advanced solid tumors
por: Mizugaki, Hidenori, et al.
Publicado: (2016)

Two Cases of Atezolizumab-Induced Hypophysitis
por: Kanie, Keitaro, et al.
Publicado: (2017)

Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy
por: Lambert, Nicolas, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_24fhpiqcaef7om530tus574ef8