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Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus
OBJECTIVES: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic–erosive oral lichen planus. MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485432/ https://www.ncbi.nlm.nih.gov/pubmed/37694075 http://dx.doi.org/10.4103/jpbs.jpbs_127_23 |
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author | Bajoria, Atul Anand Chinnannavar, Sangamesh Ningappa Mishra, Silpiranjan Singh, Dhirendra K. Pathi, Jugajyoti Jha, Vikash K. |
author_facet | Bajoria, Atul Anand Chinnannavar, Sangamesh Ningappa Mishra, Silpiranjan Singh, Dhirendra K. Pathi, Jugajyoti Jha, Vikash K. |
author_sort | Bajoria, Atul Anand |
collection | PubMed |
description | OBJECTIVES: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic–erosive oral lichen planus. MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered in the present study. Subjects were classified into two groups. Group I: Patients in this group were treated with 1% pimecrolimus cream and Group II: Patients falling under this group were treated with triamcinolone acetonide in 0.1% concentration. RESULTS: None of the patients reported worsening clinical signs and symptoms. No significant difference in efficacy and reduction in burning sensation of either pimecrolimus or trimcinolone acetonide was present. CONCLUSION: Present study found no significant difference in the efficacy of both the agents studied. |
format | Online Article Text |
id | pubmed-10485432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-104854322023-09-09 Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus Bajoria, Atul Anand Chinnannavar, Sangamesh Ningappa Mishra, Silpiranjan Singh, Dhirendra K. Pathi, Jugajyoti Jha, Vikash K. J Pharm Bioallied Sci Original Article OBJECTIVES: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic–erosive oral lichen planus. MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered in the present study. Subjects were classified into two groups. Group I: Patients in this group were treated with 1% pimecrolimus cream and Group II: Patients falling under this group were treated with triamcinolone acetonide in 0.1% concentration. RESULTS: None of the patients reported worsening clinical signs and symptoms. No significant difference in efficacy and reduction in burning sensation of either pimecrolimus or trimcinolone acetonide was present. CONCLUSION: Present study found no significant difference in the efficacy of both the agents studied. Wolters Kluwer - Medknow 2023-07 2023-04-28 /pmc/articles/PMC10485432/ /pubmed/37694075 http://dx.doi.org/10.4103/jpbs.jpbs_127_23 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Bajoria, Atul Anand Chinnannavar, Sangamesh Ningappa Mishra, Silpiranjan Singh, Dhirendra K. Pathi, Jugajyoti Jha, Vikash K. Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus |
title | Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus |
title_full | Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus |
title_fullStr | Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus |
title_full_unstemmed | Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus |
title_short | Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus |
title_sort | comparative evaluation of pimecrolimus cream 1% and triamcinolone aceonide paste in treatment of atrophic–erosive oral lichen planus |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485432/ https://www.ncbi.nlm.nih.gov/pubmed/37694075 http://dx.doi.org/10.4103/jpbs.jpbs_127_23 |
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