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Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus

OBJECTIVES: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic–erosive oral lichen planus. MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered i...

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Autores principales: Bajoria, Atul Anand, Chinnannavar, Sangamesh Ningappa, Mishra, Silpiranjan, Singh, Dhirendra K., Pathi, Jugajyoti, Jha, Vikash K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485432/
https://www.ncbi.nlm.nih.gov/pubmed/37694075
http://dx.doi.org/10.4103/jpbs.jpbs_127_23
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author Bajoria, Atul Anand
Chinnannavar, Sangamesh Ningappa
Mishra, Silpiranjan
Singh, Dhirendra K.
Pathi, Jugajyoti
Jha, Vikash K.
author_facet Bajoria, Atul Anand
Chinnannavar, Sangamesh Ningappa
Mishra, Silpiranjan
Singh, Dhirendra K.
Pathi, Jugajyoti
Jha, Vikash K.
author_sort Bajoria, Atul Anand
collection PubMed
description OBJECTIVES: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic–erosive oral lichen planus. MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered in the present study. Subjects were classified into two groups. Group I: Patients in this group were treated with 1% pimecrolimus cream and Group II: Patients falling under this group were treated with triamcinolone acetonide in 0.1% concentration. RESULTS: None of the patients reported worsening clinical signs and symptoms. No significant difference in efficacy and reduction in burning sensation of either pimecrolimus or trimcinolone acetonide was present. CONCLUSION: Present study found no significant difference in the efficacy of both the agents studied.
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spelling pubmed-104854322023-09-09 Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus Bajoria, Atul Anand Chinnannavar, Sangamesh Ningappa Mishra, Silpiranjan Singh, Dhirendra K. Pathi, Jugajyoti Jha, Vikash K. J Pharm Bioallied Sci Original Article OBJECTIVES: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic–erosive oral lichen planus. MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered in the present study. Subjects were classified into two groups. Group I: Patients in this group were treated with 1% pimecrolimus cream and Group II: Patients falling under this group were treated with triamcinolone acetonide in 0.1% concentration. RESULTS: None of the patients reported worsening clinical signs and symptoms. No significant difference in efficacy and reduction in burning sensation of either pimecrolimus or trimcinolone acetonide was present. CONCLUSION: Present study found no significant difference in the efficacy of both the agents studied. Wolters Kluwer - Medknow 2023-07 2023-04-28 /pmc/articles/PMC10485432/ /pubmed/37694075 http://dx.doi.org/10.4103/jpbs.jpbs_127_23 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Bajoria, Atul Anand
Chinnannavar, Sangamesh Ningappa
Mishra, Silpiranjan
Singh, Dhirendra K.
Pathi, Jugajyoti
Jha, Vikash K.
Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus
title Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus
title_full Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus
title_fullStr Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus
title_full_unstemmed Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus
title_short Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic–Erosive Oral Lichen Planus
title_sort comparative evaluation of pimecrolimus cream 1% and triamcinolone aceonide paste in treatment of atrophic–erosive oral lichen planus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485432/
https://www.ncbi.nlm.nih.gov/pubmed/37694075
http://dx.doi.org/10.4103/jpbs.jpbs_127_23
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