Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus

OBJECTIVES: Compare 5% amlexanox, 0.1% triamcinolone acetonide, and 0.03% tacrolimus in the management of oral lichen planus (OLP). MATERIALS AND METHODS: A received 0.03% tacrolimus, group B received 0.1% triamcinolone acetonide and group C received topical 5% amlexanox. All patients were evaluated...

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Detalles Bibliográficos
Autores principales: AlMutairi, Mohammed, Riyaz, SS Mohamed Abdulcader, Awinashe, Minal, Almutairi, Faris Jaser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485504/
https://www.ncbi.nlm.nih.gov/pubmed/37693973
http://dx.doi.org/10.4103/jpbs.jpbs_112_23
Descripción
Sumario:OBJECTIVES: Compare 5% amlexanox, 0.1% triamcinolone acetonide, and 0.03% tacrolimus in the management of oral lichen planus (OLP). MATERIALS AND METHODS: A received 0.03% tacrolimus, group B received 0.1% triamcinolone acetonide and group C received topical 5% amlexanox. All patients were evaluated for pain on visual analog scale (VAS) and erosive area on day 1, 7, and 15. RESULTS: There was decrease in visual analogue score (VAS) for pain in all tested group after 15 days. There was significant decrease in erosive area in left and right buccal mucosa in all groups after 15 days for inter and intra group comparison. CONCLUSION: All the drugs used were effective in management of patients with OLP and thus it can be advised to consider these agents as alternatives.

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