Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus

OBJECTIVES: Compare 5% amlexanox, 0.1% triamcinolone acetonide, and 0.03% tacrolimus in the management of oral lichen planus (OLP). MATERIALS AND METHODS: A received 0.03% tacrolimus, group B received 0.1% triamcinolone acetonide and group C received topical 5% amlexanox. All patients were evaluated...

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Autores principales: AlMutairi, Mohammed, Riyaz, SS Mohamed Abdulcader, Awinashe, Minal, Almutairi, Faris Jaser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485504/
https://www.ncbi.nlm.nih.gov/pubmed/37693973
http://dx.doi.org/10.4103/jpbs.jpbs_112_23
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author AlMutairi, Mohammed
Riyaz, SS Mohamed Abdulcader
Awinashe, Minal
Almutairi, Faris Jaser
author_facet AlMutairi, Mohammed
Riyaz, SS Mohamed Abdulcader
Awinashe, Minal
Almutairi, Faris Jaser
author_sort AlMutairi, Mohammed
collection PubMed
description OBJECTIVES: Compare 5% amlexanox, 0.1% triamcinolone acetonide, and 0.03% tacrolimus in the management of oral lichen planus (OLP). MATERIALS AND METHODS: A received 0.03% tacrolimus, group B received 0.1% triamcinolone acetonide and group C received topical 5% amlexanox. All patients were evaluated for pain on visual analog scale (VAS) and erosive area on day 1, 7, and 15. RESULTS: There was decrease in visual analogue score (VAS) for pain in all tested group after 15 days. There was significant decrease in erosive area in left and right buccal mucosa in all groups after 15 days for inter and intra group comparison. CONCLUSION: All the drugs used were effective in management of patients with OLP and thus it can be advised to consider these agents as alternatives.
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spelling pubmed-104855042023-09-09 Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus AlMutairi, Mohammed Riyaz, SS Mohamed Abdulcader Awinashe, Minal Almutairi, Faris Jaser J Pharm Bioallied Sci Original Article OBJECTIVES: Compare 5% amlexanox, 0.1% triamcinolone acetonide, and 0.03% tacrolimus in the management of oral lichen planus (OLP). MATERIALS AND METHODS: A received 0.03% tacrolimus, group B received 0.1% triamcinolone acetonide and group C received topical 5% amlexanox. All patients were evaluated for pain on visual analog scale (VAS) and erosive area on day 1, 7, and 15. RESULTS: There was decrease in visual analogue score (VAS) for pain in all tested group after 15 days. There was significant decrease in erosive area in left and right buccal mucosa in all groups after 15 days for inter and intra group comparison. CONCLUSION: All the drugs used were effective in management of patients with OLP and thus it can be advised to consider these agents as alternatives. Wolters Kluwer - Medknow 2023-07 2023-04-28 /pmc/articles/PMC10485504/ /pubmed/37693973 http://dx.doi.org/10.4103/jpbs.jpbs_112_23 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
AlMutairi, Mohammed
Riyaz, SS Mohamed Abdulcader
Awinashe, Minal
Almutairi, Faris Jaser
Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus
title Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus
title_full Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus
title_fullStr Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus
title_full_unstemmed Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus
title_short Assessment of 5% Amlexanox, 0.1% Triamcinolone Acetonide and 0.03% Tacrolimus in the Management of Oral Lichen Planus
title_sort assessment of 5% amlexanox, 0.1% triamcinolone acetonide and 0.03% tacrolimus in the management of oral lichen planus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485504/
https://www.ncbi.nlm.nih.gov/pubmed/37693973
http://dx.doi.org/10.4103/jpbs.jpbs_112_23
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