Cargando…

A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis

AIM: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS). MATERIALS AND METHODS: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were...

Descripción completa

Detalles Bibliográficos
Autores principales: Rakhee, Kumar, Vivek, Singh, Chintu Kumar, Arvind, Ananya, Ahsan, Aasia, Kumar, Sudhanshu, Das, Debeswar, Kumari, Subham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485544/
https://www.ncbi.nlm.nih.gov/pubmed/37693963
http://dx.doi.org/10.4103/jpbs.jpbs_102_23
_version_ 1785102811460009984
author Rakhee
Kumar, Vivek
Singh, Chintu Kumar
Arvind, Ananya
Ahsan, Aasia
Kumar, Sudhanshu
Das, Debeswar
Kumari, Subham
author_facet Rakhee
Kumar, Vivek
Singh, Chintu Kumar
Arvind, Ananya
Ahsan, Aasia
Kumar, Sudhanshu
Das, Debeswar
Kumari, Subham
author_sort Rakhee
collection PubMed
description AIM: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS). MATERIALS AND METHODS: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were randomly divided into two groups—the dexamethasone ointment group (Group I) and the triamcinolone acetonide gel group (Group II). Patients were asked to apply the gel three times a day on each ulcer. Estimation of the efficacy of gel was done based on the time required for regression in pain, size, and number of ulcers. RESULTS: The results showed there was a significant difference in size, pain, number, and duration of ulcers in Group I and Group II within 7 days. However, in both groups, no significant difference was noted in the treatment of RAS. CONCLUSION: Dexamethasone ointment was found to be efficient in this treatment and was safe as evaluated using clinical assessments.
format Online
Article
Text
id pubmed-10485544
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-104855442023-09-09 A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis Rakhee Kumar, Vivek Singh, Chintu Kumar Arvind, Ananya Ahsan, Aasia Kumar, Sudhanshu Das, Debeswar Kumari, Subham J Pharm Bioallied Sci Original Article AIM: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS). MATERIALS AND METHODS: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were randomly divided into two groups—the dexamethasone ointment group (Group I) and the triamcinolone acetonide gel group (Group II). Patients were asked to apply the gel three times a day on each ulcer. Estimation of the efficacy of gel was done based on the time required for regression in pain, size, and number of ulcers. RESULTS: The results showed there was a significant difference in size, pain, number, and duration of ulcers in Group I and Group II within 7 days. However, in both groups, no significant difference was noted in the treatment of RAS. CONCLUSION: Dexamethasone ointment was found to be efficient in this treatment and was safe as evaluated using clinical assessments. Wolters Kluwer - Medknow 2023-07 2023-04-28 /pmc/articles/PMC10485544/ /pubmed/37693963 http://dx.doi.org/10.4103/jpbs.jpbs_102_23 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Rakhee
Kumar, Vivek
Singh, Chintu Kumar
Arvind, Ananya
Ahsan, Aasia
Kumar, Sudhanshu
Das, Debeswar
Kumari, Subham
A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis
title A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis
title_full A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis
title_fullStr A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis
title_full_unstemmed A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis
title_short A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis
title_sort comparative study of dexamethasone ointment along with triamcinolone acetonide in treatment of recurrent aphthous stomatitis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485544/
https://www.ncbi.nlm.nih.gov/pubmed/37693963
http://dx.doi.org/10.4103/jpbs.jpbs_102_23
work_keys_str_mv AT rakhee acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT kumarvivek acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT singhchintukumar acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT arvindananya acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT ahsanaasia acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT kumarsudhanshu acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT dasdebeswar acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT kumarisubham acomparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT rakhee comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT kumarvivek comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT singhchintukumar comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT arvindananya comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT ahsanaasia comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT kumarsudhanshu comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT dasdebeswar comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis
AT kumarisubham comparativestudyofdexamethasoneointmentalongwithtriamcinoloneacetonideintreatmentofrecurrentaphthousstomatitis