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A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis
AIM: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS). MATERIALS AND METHODS: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer - Medknow
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485544/ https://www.ncbi.nlm.nih.gov/pubmed/37693963 http://dx.doi.org/10.4103/jpbs.jpbs_102_23 |
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author | Rakhee Kumar, Vivek Singh, Chintu Kumar Arvind, Ananya Ahsan, Aasia Kumar, Sudhanshu Das, Debeswar Kumari, Subham |
author_facet | Rakhee Kumar, Vivek Singh, Chintu Kumar Arvind, Ananya Ahsan, Aasia Kumar, Sudhanshu Das, Debeswar Kumari, Subham |
author_sort | Rakhee |
collection | PubMed |
description | AIM: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS). MATERIALS AND METHODS: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were randomly divided into two groups—the dexamethasone ointment group (Group I) and the triamcinolone acetonide gel group (Group II). Patients were asked to apply the gel three times a day on each ulcer. Estimation of the efficacy of gel was done based on the time required for regression in pain, size, and number of ulcers. RESULTS: The results showed there was a significant difference in size, pain, number, and duration of ulcers in Group I and Group II within 7 days. However, in both groups, no significant difference was noted in the treatment of RAS. CONCLUSION: Dexamethasone ointment was found to be efficient in this treatment and was safe as evaluated using clinical assessments. |
format | Online Article Text |
id | pubmed-10485544 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-104855442023-09-09 A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis Rakhee Kumar, Vivek Singh, Chintu Kumar Arvind, Ananya Ahsan, Aasia Kumar, Sudhanshu Das, Debeswar Kumari, Subham J Pharm Bioallied Sci Original Article AIM: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS). MATERIALS AND METHODS: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were randomly divided into two groups—the dexamethasone ointment group (Group I) and the triamcinolone acetonide gel group (Group II). Patients were asked to apply the gel three times a day on each ulcer. Estimation of the efficacy of gel was done based on the time required for regression in pain, size, and number of ulcers. RESULTS: The results showed there was a significant difference in size, pain, number, and duration of ulcers in Group I and Group II within 7 days. However, in both groups, no significant difference was noted in the treatment of RAS. CONCLUSION: Dexamethasone ointment was found to be efficient in this treatment and was safe as evaluated using clinical assessments. Wolters Kluwer - Medknow 2023-07 2023-04-28 /pmc/articles/PMC10485544/ /pubmed/37693963 http://dx.doi.org/10.4103/jpbs.jpbs_102_23 Text en Copyright: © 2023 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Rakhee Kumar, Vivek Singh, Chintu Kumar Arvind, Ananya Ahsan, Aasia Kumar, Sudhanshu Das, Debeswar Kumari, Subham A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis |
title | A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis |
title_full | A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis |
title_fullStr | A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis |
title_full_unstemmed | A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis |
title_short | A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis |
title_sort | comparative study of dexamethasone ointment along with triamcinolone acetonide in treatment of recurrent aphthous stomatitis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485544/ https://www.ncbi.nlm.nih.gov/pubmed/37693963 http://dx.doi.org/10.4103/jpbs.jpbs_102_23 |
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