Cargando…

Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?

INTRODUCTION: Congenital melanocytic nevi (CMN) are benign lesions composed of clonal proliferations of melanocytes. Although medium-sized CMN are common and generally remain benign throughout a person’s lifetime, they may be precursors of melanoma. There is a limited number of studies focused on th...

Descripción completa

Detalles Bibliográficos
Autores principales: Mateuszczyk, Mateusz K., Świerczyńska-Mróz, Karolina, Chlebicka, Iwona, Szepietowski, Jacek C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485756/
https://www.ncbi.nlm.nih.gov/pubmed/37692272
http://dx.doi.org/10.5114/ada.2023.128718
_version_ 1785102857626714112
author Mateuszczyk, Mateusz K.
Świerczyńska-Mróz, Karolina
Chlebicka, Iwona
Szepietowski, Jacek C.
author_facet Mateuszczyk, Mateusz K.
Świerczyńska-Mróz, Karolina
Chlebicka, Iwona
Szepietowski, Jacek C.
author_sort Mateuszczyk, Mateusz K.
collection PubMed
description INTRODUCTION: Congenital melanocytic nevi (CMN) are benign lesions composed of clonal proliferations of melanocytes. Although medium-sized CMN are common and generally remain benign throughout a person’s lifetime, they may be precursors of melanoma. There is a limited number of studies focused on the risk of melanoma in solitary, medium-sized, congenital melanocytic nevus; therefore, the incidence of malignant transformation and guidelines for treatment are not well established. AIM: Prompted by the limited data, we conducted this study to gather more information about medium-sized CMN, to optimize clinical care. We share our analysis of surgically removed medium-sized CMN. MATERIAL AND METHODS: A total of 10 patients with non-multiple, medium-sized, congenital melanocytic nevus were included in this study. Lesions were removed using surgical procedures. RESULTS: In most of the cases the reason for excision of the medium-sized CMN was evolution of the lesion or aesthetic considerations reported by the patients. In 2 cases, due to the large size of the lesions, serial excisions were performed, while other CMN were removed surgically using simple excision technique. Eight of 10 medium-sized CMN were histologically described as benign, and 2 cases of malignant transformations were reported. CONCLUSIONS: According to our clinical experience and knowledge, we recommend managing patients on an individual basis, taking into consideration multiple clinical attributes. In our opinion, long-lasting observation is the management of choice, and if there is need of surgery, we recommend total simple or staged excision depending on nevus size.
format Online
Article
Text
id pubmed-10485756
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-104857562023-09-09 Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up? Mateuszczyk, Mateusz K. Świerczyńska-Mróz, Karolina Chlebicka, Iwona Szepietowski, Jacek C. Postepy Dermatol Alergol Original Paper INTRODUCTION: Congenital melanocytic nevi (CMN) are benign lesions composed of clonal proliferations of melanocytes. Although medium-sized CMN are common and generally remain benign throughout a person’s lifetime, they may be precursors of melanoma. There is a limited number of studies focused on the risk of melanoma in solitary, medium-sized, congenital melanocytic nevus; therefore, the incidence of malignant transformation and guidelines for treatment are not well established. AIM: Prompted by the limited data, we conducted this study to gather more information about medium-sized CMN, to optimize clinical care. We share our analysis of surgically removed medium-sized CMN. MATERIAL AND METHODS: A total of 10 patients with non-multiple, medium-sized, congenital melanocytic nevus were included in this study. Lesions were removed using surgical procedures. RESULTS: In most of the cases the reason for excision of the medium-sized CMN was evolution of the lesion or aesthetic considerations reported by the patients. In 2 cases, due to the large size of the lesions, serial excisions were performed, while other CMN were removed surgically using simple excision technique. Eight of 10 medium-sized CMN were histologically described as benign, and 2 cases of malignant transformations were reported. CONCLUSIONS: According to our clinical experience and knowledge, we recommend managing patients on an individual basis, taking into consideration multiple clinical attributes. In our opinion, long-lasting observation is the management of choice, and if there is need of surgery, we recommend total simple or staged excision depending on nevus size. Termedia Publishing House 2023-06-18 2023-08 /pmc/articles/PMC10485756/ /pubmed/37692272 http://dx.doi.org/10.5114/ada.2023.128718 Text en Copyright: © 2023 Termedia Sp. z o. o. https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Mateuszczyk, Mateusz K.
Świerczyńska-Mróz, Karolina
Chlebicka, Iwona
Szepietowski, Jacek C.
Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?
title Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?
title_full Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?
title_fullStr Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?
title_full_unstemmed Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?
title_short Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?
title_sort non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485756/
https://www.ncbi.nlm.nih.gov/pubmed/37692272
http://dx.doi.org/10.5114/ada.2023.128718
work_keys_str_mv AT mateuszczykmateuszk nonmultiplemediumsizedcongenitalmelanocyticnevitoexciseortofollowup
AT swierczynskamrozkarolina nonmultiplemediumsizedcongenitalmelanocyticnevitoexciseortofollowup
AT chlebickaiwona nonmultiplemediumsizedcongenitalmelanocyticnevitoexciseortofollowup
AT szepietowskijacekc nonmultiplemediumsizedcongenitalmelanocyticnevitoexciseortofollowup