Efficient DNA knock-in using AAV-mediated delivery with 2-cell embryo CRISPR-Cas9 electroporation

Recent advances in CRISPR-Cas genome editing technology have been instrumental in improving the efficiency to produce genetically modified animal models. In this study we have combined four very promising approaches to come up with a highly effective pipeline to produce knock-in mouse and rat models...

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Detalles Bibliográficos
Autores principales: Davis, Daniel J., McNew, James F., Maresca-Fichter, Hailey, Chen, Kaiwen, Telugu, Bhanu P., Bryda, Elizabeth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485772/
https://www.ncbi.nlm.nih.gov/pubmed/37694158
http://dx.doi.org/10.3389/fgeed.2023.1256451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485772/
https://www.ncbi.nlm.nih.gov/pubmed/37694158
http://dx.doi.org/10.3389/fgeed.2023.1256451

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