Cargando…

The actin-bundling protein Fascin-1 modulates ciliary signalling

Primary cilia are microtubule-based cell organelles important for cellular communication. Since they are involved in the regulation of numerous signalling pathways, defects in cilia development or function are associated with genetic disorders, collectively called ciliopathies. Besides their ciliary...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brücker, Lena, Becker, Stefanie Kornelia, Maissl, Vanessa, Harms, Gregory, Parsons, Maddy, May-Simera, Helen Louise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485897/ https://www.ncbi.nlm.nih.gov/pubmed/37015875 http://dx.doi.org/10.1093/jmcb/mjad022

Ejemplares similares

Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
por: Ewerling, Alexander, et al.
Publicado: (2023)

Fascin promotes filopodia formation independent of its role in actin bundling
por: Zanet, Jennifer, et al.
Publicado: (2012)

Fascin in Cell Migration: More Than an Actin Bundling Protein
por: Lamb, Maureen C., et al.
Publicado: (2020)

Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia cross-linker fascin
por: Harker, Alyssa J., et al.
Publicado: (2019)

Inhibitors of the Actin-Bundling Protein Fascin-1 Developed for Tumor Therapy Attenuate the T-Cell Stimulatory Properties of Dendritic Cells
por: Zeyn, Yanira, et al.
Publicado: (2022)

IKKε inhibits PKC to promote Fascin-dependent actin bundling
por: Otani, Tetsuhisa, et al.
Publicado: (2016)

The Actin Bundling Protein Fascin-1 as an ACE2-Accessory Protein
por: Ogunlade, Blessing, et al.
Publicado: (2020)

Strong fascin expression promotes metastasis independent of its F-actin bundling activity
por: Heinz, Lisa S., et al.
Publicado: (2017)

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability
por: Jayo, Asier, et al.
Publicado: (2012)

beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex
Publicado: (1996)

Structural Analysis of Human Fascin-1: Essential Protein for Actin Filaments Bundling
por: Chung, Jeong Min, et al.
Publicado: (2022)

Cooperative bundling by fascin generates actin structures with architectures that depend on filament length
por: Sherer, Laura A., et al.
Publicado: (2022)

Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target?
por: Liu, Hongliang, et al.
Publicado: (2021)

The actin bundling protein Fascin is important for proper early development in Strongylocentrotus purpuratus embryos
por: Testa, Michael D., et al.
Publicado: (2023)

Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breastancer
por: Grothey, A, et al.
Publicado: (2000)

The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro
por: Qualtrough, D, et al.
Publicado: (2009)

The actin-bundling protein Fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair
por: Qualtrough, David, et al.
Publicado: (2011)

The Chlamydia trachomatis Early Effector Tarp Outcompetes Fascin in Forming F-Actin Bundles In Vivo
por: Aranjuez, George F., et al.
Publicado: (2022)

Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension
Publicado: (1994)

MiR-145 Inhibits Metastasis by Targeting Fascin Actin-Bundling Protein 1 in Nasopharyngeal Carcinoma
por: Li, Ying-Qin, et al.
Publicado: (2015)

Confinement Geometry Tunes Fascin-Actin Bundle Structures and Consequently the Shape of a Lipid Bilayer Vesicle
por: Bashirzadeh, Yashar, et al.
Publicado: (2020)

Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture
por: Groen, Christopher M., et al.
Publicado: (2015)

FMNL2 regulates dynamics of fascin in filopodia
por: Pfisterer, Karin, et al.
Publicado: (2020)

Nuclear fascin regulates cancer cell survival
por: Lawson, Campbell D, et al.
Publicado: (2022)

Fascin regulates nuclear actin during Drosophila oogenesis
por: Kelpsch, Daniel J., et al.
Publicado: (2016)

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells
por: Jayo, Asier, et al.
Publicado: (2016)

Fascin lysine 471 acetylation cooperates with serine 39 phosphorylation to inhibit actin‐bundling activity and tumor metastasis in esophageal squamous cell carcinoma
por: Zeng, Fa‐Min, et al.
Publicado: (2022)

A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration
por: Villari, Giulia, et al.
Publicado: (2015)

The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1)
por: Gross, Christine, et al.
Publicado: (2016)

MicroRNA-133a inhibits proliferation and invasion, and induces apoptosis in gastric carcinoma cells via targeting fascin actin-bundling protein 1
por: Lai, Chen, et al.
Publicado: (2021)

Loss of Ciliary Gene Bbs8 Results in Physiological Defects in the Retinal Pigment Epithelium
por: Schneider, Sandra, et al.
Publicado: (2021)

P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer
por: Cheng, Yin‐Wei, et al.
Publicado: (2021)

Fascin 2b Is a Component of Stereocilia that Lengthens Actin-Based Protrusions
por: Chou, Shih-Wei, et al.
Publicado: (2011)

Fascin-induced actin protrusions are suppressed by dendritic networks in giant unilamellar vesicles
por: Wubshet, Nadab H., et al.
Publicado: (2021)

Control of nuclear organization by F-actin binding proteins
por: Pfisterer, Karin, et al.
Publicado: (2017)

Proteases are Modulated by Fascin in Oral Cancer Invasion
por: Lee, Min Kyeong, et al.
Publicado: (2018)

Single Actin Bundle Rheology
por: Strehle, Dan, et al.
Publicado: (2017)

Actin Bundles in The Pollen Tube
por: Zhang, Shujuan, et al.
Publicado: (2018)

Computing on actin bundles network
por: Adamatzky, Andrew, et al.
Publicado: (2019)

Actin Bundles Dynamics and Architecture
por: Rajan, Sudeepa, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_od37qmmvjvp5ppp86haedfda3n