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Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series

Fat embolism syndrome (FES) is a rare but potentially fatal complication of trauma or orthopaedic surgery, which presents predominantly with pulmonary symptoms. The rapid worsening respiratory failure in a previously normal orthopaedic surgery or trauma patients usually get evaluated for pulmonary e...

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Autores principales: Williams, Benjamin Earnest, Nair, Avinash A., James, Prince, Isaac, Barney, Gupta, Richa, Ashok, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485911/
https://www.ncbi.nlm.nih.gov/pubmed/37692762
http://dx.doi.org/10.1002/rcr2.1214
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author Williams, Benjamin Earnest
Nair, Avinash A.
James, Prince
Isaac, Barney
Gupta, Richa
Ashok, Anand
author_facet Williams, Benjamin Earnest
Nair, Avinash A.
James, Prince
Isaac, Barney
Gupta, Richa
Ashok, Anand
author_sort Williams, Benjamin Earnest
collection PubMed
description Fat embolism syndrome (FES) is a rare but potentially fatal complication of trauma or orthopaedic surgery, which presents predominantly with pulmonary symptoms. The rapid worsening respiratory failure in a previously normal orthopaedic surgery or trauma patients usually get evaluated for pulmonary embolism, fat‐embolism‐related acute respiratory distress or transfusion related acute lung injury. Orthopaedic surgeons and clinicians need to be aware of related entity termed ‘Fat Embolism related Diffuse Alveolar Haemorrhage’ (FEDAH). The clinical presentation in an orthopaedic surgery of trauma patient with FEDAH are haemoptysis, worsening type 1 respiratory failure and oxygen requirement, drop in haemoglobin levels with chest x‐ray/computed tomography suggestive of Diffuse alveolar haemorrhage (DAH). Early bronchoscopy and bronchoalveolar lavage (BAL) confirmation of DAH, presence of BAL haemosiderophages and lipid‐laden macrophages are the pointers in the early diagnosis of FEDAH. It needs a high clinical suspicion and interdepartmental collaborative measures. Timely referral from orthopaedic surgeons, early bronchoscopy and treatment with steroids is key in diagnosis and management.
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spelling pubmed-104859112023-09-09 Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series Williams, Benjamin Earnest Nair, Avinash A. James, Prince Isaac, Barney Gupta, Richa Ashok, Anand Respirol Case Rep Case Series Fat embolism syndrome (FES) is a rare but potentially fatal complication of trauma or orthopaedic surgery, which presents predominantly with pulmonary symptoms. The rapid worsening respiratory failure in a previously normal orthopaedic surgery or trauma patients usually get evaluated for pulmonary embolism, fat‐embolism‐related acute respiratory distress or transfusion related acute lung injury. Orthopaedic surgeons and clinicians need to be aware of related entity termed ‘Fat Embolism related Diffuse Alveolar Haemorrhage’ (FEDAH). The clinical presentation in an orthopaedic surgery of trauma patient with FEDAH are haemoptysis, worsening type 1 respiratory failure and oxygen requirement, drop in haemoglobin levels with chest x‐ray/computed tomography suggestive of Diffuse alveolar haemorrhage (DAH). Early bronchoscopy and bronchoalveolar lavage (BAL) confirmation of DAH, presence of BAL haemosiderophages and lipid‐laden macrophages are the pointers in the early diagnosis of FEDAH. It needs a high clinical suspicion and interdepartmental collaborative measures. Timely referral from orthopaedic surgeons, early bronchoscopy and treatment with steroids is key in diagnosis and management. John Wiley & Sons, Ltd 2023-09-08 /pmc/articles/PMC10485911/ /pubmed/37692762 http://dx.doi.org/10.1002/rcr2.1214 Text en © 2023 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Series
Williams, Benjamin Earnest
Nair, Avinash A.
James, Prince
Isaac, Barney
Gupta, Richa
Ashok, Anand
Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series
title Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series
title_full Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series
title_fullStr Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series
title_full_unstemmed Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series
title_short Fat emboli—Related diffuse alveolar haemorrhage (FEDAH) an acronym to remember—Case series
title_sort fat emboli—related diffuse alveolar haemorrhage (fedah) an acronym to remember—case series
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485911/
https://www.ncbi.nlm.nih.gov/pubmed/37692762
http://dx.doi.org/10.1002/rcr2.1214
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