GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice

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BACKGROUND: Neonatal hyperoxia exposure is associated with brain injury and poor neurodevelopment outcomes in preterm infants. Our previous studies in neonatal rodent models have shown that hyperoxia stimulates the brain’s inflammasome pathway, leading to the activation of gasdermin D (GSDMD), a key...

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Detalles Bibliográficos
Autores principales: Challa, Naga Venkata Divya, Chen, Shaoyi, Yuan, Huijun, Duncan, Matthew R., Moreno, William Javier, Bramlett, Helen, Dietrich, W. Dalton, Benny, Merline, Schmidt, Augusto F., Young, Karen, Wu, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486051/
https://www.ncbi.nlm.nih.gov/pubmed/37679766
http://dx.doi.org/10.1186/s12974-023-02878-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486051/
https://www.ncbi.nlm.nih.gov/pubmed/37679766
http://dx.doi.org/10.1186/s12974-023-02878-8

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