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GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice
BACKGROUND: Neonatal hyperoxia exposure is associated with brain injury and poor neurodevelopment outcomes in preterm infants. Our previous studies in neonatal rodent models have shown that hyperoxia stimulates the brain’s inflammasome pathway, leading to the activation of gasdermin D (GSDMD), a key...
Autores principales: | Challa, Naga Venkata Divya, Chen, Shaoyi, Yuan, Huijun, Duncan, Matthew R., Moreno, William Javier, Bramlett, Helen, Dietrich, W. Dalton, Benny, Merline, Schmidt, Augusto F., Young, Karen, Wu, Shu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486051/ https://www.ncbi.nlm.nih.gov/pubmed/37679766 http://dx.doi.org/10.1186/s12974-023-02878-8 |
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