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Positron emission tomography imaging of the sodium iodide symporter senses real-time energy stress in vivo

BACKGROUND: Tissue environment is critical in determining tumour metabolic vulnerability. However, in vivo drug testing is slow and waiting for tumour growth delay may not be the most appropriate endpoint for metabolic treatments. An in vivo method for measuring energy stress would rapidly determine...

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Detalles Bibliográficos
Autores principales: Dzien, Piotr, Mackintosh, Agata, Malviya, Gaurav, Johnson, Emma, Soloviev, Dmitry, Brown, Gavin, Uribe, Alejandro Huerta, Nixon, Colin, Lyons, Scott K., Maddocks, Oliver, Blyth, Karen, Lewis, David Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486058/
https://www.ncbi.nlm.nih.gov/pubmed/37679822
http://dx.doi.org/10.1186/s40170-023-00314-2