In vitro-generated human muscle reserve cells are heterogeneous for Pax7 with distinct molecular states and metabolic profiles

BACKGROUND: The capacity of skeletal muscles to regenerate relies on Pax7(+) muscle stem cells (MuSC). While in vitro-amplified MuSC are activated and lose part of their regenerative capacity, in vitro-generated human muscle reserve cells (MuRC) are very similar to quiescent MuSC with properties req...

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Detalles Bibliográficos
Autores principales: Bouche, Axelle, Borner, Benoit, Richard, Chloé, Grand, Ysaline, Hannouche, Didier, Laumonier, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486062/
https://www.ncbi.nlm.nih.gov/pubmed/37679820
http://dx.doi.org/10.1186/s13287-023-03483-5

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