SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation

BACKGROUND: Neoadjuvant radiotherapy has been used as the standard treatment of colorectal cancer (CRC). However, radiotherapy resistance often results in treatment failure. To identify radioresistant genes will provide novel targets for combined treatments and prognostic markers. METHODS: Through h...

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Detalles Bibliográficos
Autores principales: Liu, Tingting, Wang, Hang, Chen, Yuanyuan, Wan, Zhijie, Du, Zhipeng, Shen, Hui, Yu, Yue, Ma, Shengzhe, Xu, Ying, Li, Zhuqing, Yu, Nanxi, Zhang, Fangxiao, Cao, Kun, Cai, Jianming, Zhang, Wei, Gao, Fu, Yang, Yanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486113/
https://www.ncbi.nlm.nih.gov/pubmed/37684630
http://dx.doi.org/10.1186/s13046-023-02789-9

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