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Effect of non-enzymatic glycation on collagen nanoscale mechanisms in diabetic and age-related bone fragility

Age and diabetes have long been known to induce an oxidative reaction between glucose and collagen, leading to the accumulation of advanced glycation end-products (AGEs) cross-links in collagenous tissues. More recently, AGEs content has been related to loss of bone quality, independent of bone mass...

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Detalles Bibliográficos
Autores principales: ROSENBERG, James L., WOOLLEY, William, ELNUNU, Ihsan, KAMML, Julia, KAMMER, David S., ACEVEDO, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486207/
https://www.ncbi.nlm.nih.gov/pubmed/37693278
http://dx.doi.org/10.32604/biocell.2023.028014