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Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm

BACKGROUND: Prior self-harm represents the most significant risk factor for future self-harm or suicide. AIM: To evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordination and safety planning), following a hospital-treated self...

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Autores principales: Le, Long Khanh-Dao, Flego, Anna, Krysinska, Karolina, Andriessen, Karl, Bandara, Piumee, Page, Andrew, Schlichthorst, Marisa, Pirkis, Jane, Mihalopoulos, Cathrine, Carter, Greg, Reifels, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486225/
https://www.ncbi.nlm.nih.gov/pubmed/37525591
http://dx.doi.org/10.1192/bjo.2023.525
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author Le, Long Khanh-Dao
Flego, Anna
Krysinska, Karolina
Andriessen, Karl
Bandara, Piumee
Page, Andrew
Schlichthorst, Marisa
Pirkis, Jane
Mihalopoulos, Cathrine
Carter, Greg
Reifels, Lennart
author_facet Le, Long Khanh-Dao
Flego, Anna
Krysinska, Karolina
Andriessen, Karl
Bandara, Piumee
Page, Andrew
Schlichthorst, Marisa
Pirkis, Jane
Mihalopoulos, Cathrine
Carter, Greg
Reifels, Lennart
author_sort Le, Long Khanh-Dao
collection PubMed
description BACKGROUND: Prior self-harm represents the most significant risk factor for future self-harm or suicide. AIM: To evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordination and safety planning), following a hospital-treated self-harm episode, for reducing repeated self-harm within the Australian context. METHOD: We employed economic modelling techniques to undertake: (a) a return-on-investment analysis, which compared the cost-savings generated by the intervention with the overall cost of implementing the intervention; and (b) a cost–utility analysis, which compared the net costs of the intervention with health outcomes measured in quality-adjusted life years (QALYs). We considered cost offsets associated with hospital admission for self-harm and the cost of suicide over a period of 10 years in the base case analysis. Uncertainty and one-way sensitivity analyses were also conducted. RESULTS: The brief aftercare intervention resulted in net cost-savings of AUD$7.5 M (95% uncertainty interval: −56.2 M to 15.1 M) and was associated with a gain of 222 (95% uncertainty interval: 45 to 563) QALYs over a 10-year period. The estimated return-on-investment ratio for the intervention's modelled cost in relation to cost-savings was 1.58 (95% uncertainty interval: −0.17 to 5.33). Eighty-seven per cent of uncertainty iterations showed that the intervention could be considered cost-effective, either through cost-savings or with an acceptable cost-effectiveness ratio of 50 000 per QALY gained. The results remained robust across sensitivity analyses. CONCLUSIONS: A theoretical brief aftercare intervention is highly likely to be cost-effective for preventing suicide and self-harm among individuals with a history of self-harm.
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spelling pubmed-104862252023-09-09 Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm Le, Long Khanh-Dao Flego, Anna Krysinska, Karolina Andriessen, Karl Bandara, Piumee Page, Andrew Schlichthorst, Marisa Pirkis, Jane Mihalopoulos, Cathrine Carter, Greg Reifels, Lennart BJPsych Open Paper BACKGROUND: Prior self-harm represents the most significant risk factor for future self-harm or suicide. AIM: To evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordination and safety planning), following a hospital-treated self-harm episode, for reducing repeated self-harm within the Australian context. METHOD: We employed economic modelling techniques to undertake: (a) a return-on-investment analysis, which compared the cost-savings generated by the intervention with the overall cost of implementing the intervention; and (b) a cost–utility analysis, which compared the net costs of the intervention with health outcomes measured in quality-adjusted life years (QALYs). We considered cost offsets associated with hospital admission for self-harm and the cost of suicide over a period of 10 years in the base case analysis. Uncertainty and one-way sensitivity analyses were also conducted. RESULTS: The brief aftercare intervention resulted in net cost-savings of AUD$7.5 M (95% uncertainty interval: −56.2 M to 15.1 M) and was associated with a gain of 222 (95% uncertainty interval: 45 to 563) QALYs over a 10-year period. The estimated return-on-investment ratio for the intervention's modelled cost in relation to cost-savings was 1.58 (95% uncertainty interval: −0.17 to 5.33). Eighty-seven per cent of uncertainty iterations showed that the intervention could be considered cost-effective, either through cost-savings or with an acceptable cost-effectiveness ratio of 50 000 per QALY gained. The results remained robust across sensitivity analyses. CONCLUSIONS: A theoretical brief aftercare intervention is highly likely to be cost-effective for preventing suicide and self-harm among individuals with a history of self-harm. Cambridge University Press 2023-08-01 /pmc/articles/PMC10486225/ /pubmed/37525591 http://dx.doi.org/10.1192/bjo.2023.525 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Paper
Le, Long Khanh-Dao
Flego, Anna
Krysinska, Karolina
Andriessen, Karl
Bandara, Piumee
Page, Andrew
Schlichthorst, Marisa
Pirkis, Jane
Mihalopoulos, Cathrine
Carter, Greg
Reifels, Lennart
Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
title Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
title_full Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
title_fullStr Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
title_full_unstemmed Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
title_short Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
title_sort modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
topic Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486225/
https://www.ncbi.nlm.nih.gov/pubmed/37525591
http://dx.doi.org/10.1192/bjo.2023.525
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