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Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
BACKGROUND: Prior self-harm represents the most significant risk factor for future self-harm or suicide. AIM: To evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordination and safety planning), following a hospital-treated self...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486225/ https://www.ncbi.nlm.nih.gov/pubmed/37525591 http://dx.doi.org/10.1192/bjo.2023.525 |
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author | Le, Long Khanh-Dao Flego, Anna Krysinska, Karolina Andriessen, Karl Bandara, Piumee Page, Andrew Schlichthorst, Marisa Pirkis, Jane Mihalopoulos, Cathrine Carter, Greg Reifels, Lennart |
author_facet | Le, Long Khanh-Dao Flego, Anna Krysinska, Karolina Andriessen, Karl Bandara, Piumee Page, Andrew Schlichthorst, Marisa Pirkis, Jane Mihalopoulos, Cathrine Carter, Greg Reifels, Lennart |
author_sort | Le, Long Khanh-Dao |
collection | PubMed |
description | BACKGROUND: Prior self-harm represents the most significant risk factor for future self-harm or suicide. AIM: To evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordination and safety planning), following a hospital-treated self-harm episode, for reducing repeated self-harm within the Australian context. METHOD: We employed economic modelling techniques to undertake: (a) a return-on-investment analysis, which compared the cost-savings generated by the intervention with the overall cost of implementing the intervention; and (b) a cost–utility analysis, which compared the net costs of the intervention with health outcomes measured in quality-adjusted life years (QALYs). We considered cost offsets associated with hospital admission for self-harm and the cost of suicide over a period of 10 years in the base case analysis. Uncertainty and one-way sensitivity analyses were also conducted. RESULTS: The brief aftercare intervention resulted in net cost-savings of AUD$7.5 M (95% uncertainty interval: −56.2 M to 15.1 M) and was associated with a gain of 222 (95% uncertainty interval: 45 to 563) QALYs over a 10-year period. The estimated return-on-investment ratio for the intervention's modelled cost in relation to cost-savings was 1.58 (95% uncertainty interval: −0.17 to 5.33). Eighty-seven per cent of uncertainty iterations showed that the intervention could be considered cost-effective, either through cost-savings or with an acceptable cost-effectiveness ratio of 50 000 per QALY gained. The results remained robust across sensitivity analyses. CONCLUSIONS: A theoretical brief aftercare intervention is highly likely to be cost-effective for preventing suicide and self-harm among individuals with a history of self-harm. |
format | Online Article Text |
id | pubmed-10486225 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-104862252023-09-09 Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm Le, Long Khanh-Dao Flego, Anna Krysinska, Karolina Andriessen, Karl Bandara, Piumee Page, Andrew Schlichthorst, Marisa Pirkis, Jane Mihalopoulos, Cathrine Carter, Greg Reifels, Lennart BJPsych Open Paper BACKGROUND: Prior self-harm represents the most significant risk factor for future self-harm or suicide. AIM: To evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordination and safety planning), following a hospital-treated self-harm episode, for reducing repeated self-harm within the Australian context. METHOD: We employed economic modelling techniques to undertake: (a) a return-on-investment analysis, which compared the cost-savings generated by the intervention with the overall cost of implementing the intervention; and (b) a cost–utility analysis, which compared the net costs of the intervention with health outcomes measured in quality-adjusted life years (QALYs). We considered cost offsets associated with hospital admission for self-harm and the cost of suicide over a period of 10 years in the base case analysis. Uncertainty and one-way sensitivity analyses were also conducted. RESULTS: The brief aftercare intervention resulted in net cost-savings of AUD$7.5 M (95% uncertainty interval: −56.2 M to 15.1 M) and was associated with a gain of 222 (95% uncertainty interval: 45 to 563) QALYs over a 10-year period. The estimated return-on-investment ratio for the intervention's modelled cost in relation to cost-savings was 1.58 (95% uncertainty interval: −0.17 to 5.33). Eighty-seven per cent of uncertainty iterations showed that the intervention could be considered cost-effective, either through cost-savings or with an acceptable cost-effectiveness ratio of 50 000 per QALY gained. The results remained robust across sensitivity analyses. CONCLUSIONS: A theoretical brief aftercare intervention is highly likely to be cost-effective for preventing suicide and self-harm among individuals with a history of self-harm. Cambridge University Press 2023-08-01 /pmc/articles/PMC10486225/ /pubmed/37525591 http://dx.doi.org/10.1192/bjo.2023.525 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. |
spellingShingle | Paper Le, Long Khanh-Dao Flego, Anna Krysinska, Karolina Andriessen, Karl Bandara, Piumee Page, Andrew Schlichthorst, Marisa Pirkis, Jane Mihalopoulos, Cathrine Carter, Greg Reifels, Lennart Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm |
title | Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm |
title_full | Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm |
title_fullStr | Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm |
title_full_unstemmed | Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm |
title_short | Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm |
title_sort | modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm |
topic | Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486225/ https://www.ncbi.nlm.nih.gov/pubmed/37525591 http://dx.doi.org/10.1192/bjo.2023.525 |
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