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Whole mount of adult ear skin as a model to study vascular malformations

BACKGROUND: Genetic analysis in human patients has linked mutations in PIK3CA, the catalytic subunit of PI‐3′Kinase, to sporadic incidences of vascular malformations. METHODS: We have developed a mouse model with inducible and endothelial‐specific expression of PIK3CA(H1047R), resulting in the devel...

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Detalles Bibliográficos
Autores principales:	Decker‐Rockefeller, Brandee, Li, Qingfen, Pumiglia, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Regular Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486327/ https://www.ncbi.nlm.nih.gov/pubmed/37682010 http://dx.doi.org/10.1002/ame2.12343

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