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Histomorphometric Analysis of 38 Giant Cell Tumors of Bone after Recurrence as Compared to Changes Following Denosumab Treatment

SIMPLE SUMMARY: Giant cell tumor of bone (GCTB) is an osteolytic tumor driven by an H3F3A-mutated mononuclear stromal cell with an accumulation of osteoclastic giant cells. Anti-RANKL antibody therapy with denosumab leads to morphological changes, and sarcomas have been described in association with...

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Detalles Bibliográficos
Autores principales:	Arndt, Sophia, Hartmann, Wolfgang, Rókusz, András, Leinauer, Benedikt, von Baer, Alexandra, Schultheiss, Markus, Pablik, Jessica, Fritzsche, Hagen, Mogler, Carolin, Antal, Imre, Baumhoer, Daniel, Mellert, Kevin, Möller, Peter, Szendrői, Miklós, Jundt, Gernot, Barth, Thomas F. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486357/ https://www.ncbi.nlm.nih.gov/pubmed/37686526 http://dx.doi.org/10.3390/cancers15174249

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