Down-Regulation of ABCA7 in Human Microglia, Astrocyte and THP-1 Cell Lines by Cholesterol Depletion, IL-1β and TNFα, or PMA

Adenosine triphosphate-binding cassette transporter subfamily A member 7 (ABCA7) is a major risk factor for Alzheimer’s disease. Human neural cell lines were used to investigate the regulation of ABCA7 expression by cholesterol and pro-inflammatory cytokines. Cholesterol was depleted by methyl-β-cyc...

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Detalles Bibliográficos
Autores principales: Wiener, Joel P., Desire, Sindy, Garliyev, Viktor, Lyssenko III, Nicholas, Praticò, Domenico, Lyssenko, Nicholas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486366/
https://www.ncbi.nlm.nih.gov/pubmed/37681876
http://dx.doi.org/10.3390/cells12172143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486366/
https://www.ncbi.nlm.nih.gov/pubmed/37681876
http://dx.doi.org/10.3390/cells12172143

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