Cargando…
Col1a2-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics
Rationale: The adult cardiac extracellular matrix (ECM) is largely comprised of type I collagen. In addition to serving as the primary structural support component of the cardiac ECM, type I collagen also provides an organizational platform for other ECM proteins, matricellular proteins, and signali...
Autores principales: | Bowers, Stephanie L. K., Meng, Qinghang, Kuwabara, Yasuhide, Huo, Jiuzhou, Minerath, Rachel, York, Allen J., Sargent, Michelle A., Prasad, Vikram, Saviola, Anthony J., Galindo, David Ceja, Hansen, Kirk C., Vagnozzi, Ronald J., Yutzey, Katherine E., Molkentin, Jeffery D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486458/ https://www.ncbi.nlm.nih.gov/pubmed/37681905 http://dx.doi.org/10.3390/cells12172174 |
Ejemplares similares
-
Rpl3l gene deletion in mice reduces heart weight over time
por: Grimes, Kelly M., et al.
Publicado: (2023) -
A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy
por: Kuwabara, Yasuhide, et al.
Publicado: (2023) -
An acute immune response underlies the benefit of cardiac stem cell therapy
por: Vagnozzi, Ronald J., et al.
Publicado: (2019) -
Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart
por: Khalil, Hadi, et al.
Publicado: (2019) -
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
por: Fu, Xing, et al.
Publicado: (2018)