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Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterised by progressive degeneration of the motor neurones. An expanded GGGGCC (G4C2) hexanucleotide repeat in C9orf72 is the most common genetic cause of ALS and frontotemporal dementia (FTD); therefore, the result...

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Detalles Bibliográficos
Autores principales: Dunn, Ella, Steinert, Joern R., Stone, Aelfwin, Sahota, Virender, Williams, Robin S. B., Snowden, Stuart, Augustin, Hrvoje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486503/
https://www.ncbi.nlm.nih.gov/pubmed/37681895
http://dx.doi.org/10.3390/cells12172163