Cargando…

Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization

Rationale and Objective: To evaluate the characteristic clinical and imaging findings of charcoal granuloma and suggest features that may differentiate charcoal granuloma from breast cancer. Materials and Methods: This retrospective study included 18 patients with a histologically confirmed breast c...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jeongju, Ko, Eun Young, Han, Boo-Kyung, Ko, Eun Sook, Choi, Ji Soo, Kim, Haejung, Kim, Myoung Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486575/
https://www.ncbi.nlm.nih.gov/pubmed/37685338
http://dx.doi.org/10.3390/diagnostics13172800
_version_ 1785103038982127616
author Kim, Jeongju
Ko, Eun Young
Han, Boo-Kyung
Ko, Eun Sook
Choi, Ji Soo
Kim, Haejung
Kim, Myoung Kyoung
author_facet Kim, Jeongju
Ko, Eun Young
Han, Boo-Kyung
Ko, Eun Sook
Choi, Ji Soo
Kim, Haejung
Kim, Myoung Kyoung
author_sort Kim, Jeongju
collection PubMed
description Rationale and Objective: To evaluate the characteristic clinical and imaging findings of charcoal granuloma and suggest features that may differentiate charcoal granuloma from breast cancer. Materials and Methods: This retrospective study included 18 patients with a histologically confirmed breast charcoal granuloma between 2005 and 2021 at a single institution. All patients had a history of breast surgery after ultrasound (US)-guided charcoal marking. Two radiologists analyzed the radiologic findings of charcoal granulomas, including the presence of a mass or calcification; the shape, margin and density of the masses on mammography; and the location, size, shape, margin, orientation, echogenicity, vascularity, presence of an echogenic halo, and posterior acoustic shadowing on US. In cases with available follow-up images, we also investigated whether the size and shape had changed. Results: The median interval between breast surgery and the diagnosis of charcoal granuloma was 2.3 years (range, 0.7–18.3 years). Thirteen lesions (72.2%) were detected on screening images. In 11 (61.1%) cases, the surgical incision was not made in the tattooed skin area. Mammography showed positive findings in 10/15 patients, and most lesions were isodense masses (70%). There were no cases with calcification. On US, all lesions were masses and showed a taller-than-wide orientation (61.1%), round or oval shape (55.6%), and iso- or hyperechogenicity (83.3%). Echogenic halo (27.8%) and posterior acoustic shadowing (16.7%) were uncommon. On Doppler US, only four cases (22.2%) showed increased vascularity. Most were classified as BI-RADS 3 (38.9%) or 4A (50.0%). After biopsy, 12 patients had follow-up mammography and US. The size of the lesion decreased in nine cases and remained unchanged in three cases. A decrease in the lesion size after biopsy showed a negative correlation with the interval between detection on imaging and biopsy (p = 0.04). Conclusion: Charcoal granuloma is most commonly found 2–3 years after surgery and occurs more frequently when the incision site is different from the tattooed skin area. US findings of tall and round or oval masses with iso- or hyperechogenicity without increased vascularity could help to differentiate them from malignancies.
format Online
Article
Text
id pubmed-10486575
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104865752023-09-09 Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization Kim, Jeongju Ko, Eun Young Han, Boo-Kyung Ko, Eun Sook Choi, Ji Soo Kim, Haejung Kim, Myoung Kyoung Diagnostics (Basel) Article Rationale and Objective: To evaluate the characteristic clinical and imaging findings of charcoal granuloma and suggest features that may differentiate charcoal granuloma from breast cancer. Materials and Methods: This retrospective study included 18 patients with a histologically confirmed breast charcoal granuloma between 2005 and 2021 at a single institution. All patients had a history of breast surgery after ultrasound (US)-guided charcoal marking. Two radiologists analyzed the radiologic findings of charcoal granulomas, including the presence of a mass or calcification; the shape, margin and density of the masses on mammography; and the location, size, shape, margin, orientation, echogenicity, vascularity, presence of an echogenic halo, and posterior acoustic shadowing on US. In cases with available follow-up images, we also investigated whether the size and shape had changed. Results: The median interval between breast surgery and the diagnosis of charcoal granuloma was 2.3 years (range, 0.7–18.3 years). Thirteen lesions (72.2%) were detected on screening images. In 11 (61.1%) cases, the surgical incision was not made in the tattooed skin area. Mammography showed positive findings in 10/15 patients, and most lesions were isodense masses (70%). There were no cases with calcification. On US, all lesions were masses and showed a taller-than-wide orientation (61.1%), round or oval shape (55.6%), and iso- or hyperechogenicity (83.3%). Echogenic halo (27.8%) and posterior acoustic shadowing (16.7%) were uncommon. On Doppler US, only four cases (22.2%) showed increased vascularity. Most were classified as BI-RADS 3 (38.9%) or 4A (50.0%). After biopsy, 12 patients had follow-up mammography and US. The size of the lesion decreased in nine cases and remained unchanged in three cases. A decrease in the lesion size after biopsy showed a negative correlation with the interval between detection on imaging and biopsy (p = 0.04). Conclusion: Charcoal granuloma is most commonly found 2–3 years after surgery and occurs more frequently when the incision site is different from the tattooed skin area. US findings of tall and round or oval masses with iso- or hyperechogenicity without increased vascularity could help to differentiate them from malignancies. MDPI 2023-08-29 /pmc/articles/PMC10486575/ /pubmed/37685338 http://dx.doi.org/10.3390/diagnostics13172800 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, Jeongju
Ko, Eun Young
Han, Boo-Kyung
Ko, Eun Sook
Choi, Ji Soo
Kim, Haejung
Kim, Myoung Kyoung
Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization
title Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization
title_full Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization
title_fullStr Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization
title_full_unstemmed Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization
title_short Characteristics of Breast Charcoal Granuloma: A Delayed Complication Following Tattoo Localization
title_sort characteristics of breast charcoal granuloma: a delayed complication following tattoo localization
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486575/
https://www.ncbi.nlm.nih.gov/pubmed/37685338
http://dx.doi.org/10.3390/diagnostics13172800
work_keys_str_mv AT kimjeongju characteristicsofbreastcharcoalgranulomaadelayedcomplicationfollowingtattoolocalization
AT koeunyoung characteristicsofbreastcharcoalgranulomaadelayedcomplicationfollowingtattoolocalization
AT hanbookyung characteristicsofbreastcharcoalgranulomaadelayedcomplicationfollowingtattoolocalization
AT koeunsook characteristicsofbreastcharcoalgranulomaadelayedcomplicationfollowingtattoolocalization
AT choijisoo characteristicsofbreastcharcoalgranulomaadelayedcomplicationfollowingtattoolocalization
AT kimhaejung characteristicsofbreastcharcoalgranulomaadelayedcomplicationfollowingtattoolocalization
AT kimmyoungkyoung characteristicsofbreastcharcoalgranulomaadelayedcomplicationfollowingtattoolocalization