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MiR-148a-3p Promotes Colorectal Cancer Cell Ferroptosis by Targeting SLC7A11

SIMPLE SUMMARY: The role of miR-148a-3p in colorectal cancer (CRC) is still debated. In this study, the in vitro antineoplastic effect of miR-148a-3p overexpression in the CRC model is reported. The antitumor activity of miR-148a-3p occurs through apoptosis, mitochondrial impairment, lipid peroxidat...

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Detalles Bibliográficos
Autores principales: Martino, Elisa, Balestrieri, Anna, Aragona, Francesca, Bifulco, Giovanna, Mele, Luigi, Campanile, Giuseppe, Balestrieri, Maria Luisa, D’Onofrio, Nunzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486764/
https://www.ncbi.nlm.nih.gov/pubmed/37686618
http://dx.doi.org/10.3390/cancers15174342