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Expanding the Clinical Utility of Targeted RNA Sequencing Panels beyond Gene Fusions to Complex, Intragenic Structural Rearrangements

SIMPLE SUMMARY: In blood cancers and solid tumors, genetic changes serve to initiate and promote cancer. These genetic changes can include rearrangements to genes which can alter gene function. Identification of gene rearrangements through molecular laboratory tests may help guide clinical care in p...

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Detalles Bibliográficos
Autores principales: Schieffer, Kathleen M., Moccia, Amanda, Bucknor, Brianna A., Stonerock, Eileen, Jayaraman, Vijayakumar, Jenkins, Heather, McKinney, Aimee, Koo, Selene C., Mathew, Mariam T., Mardis, Elaine R., Lee, Kristy, Reshmi, Shalini C., Cottrell, Catherine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486946/
https://www.ncbi.nlm.nih.gov/pubmed/37686670
http://dx.doi.org/10.3390/cancers15174394

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