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Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT

Prostate cancer still represents one of the most frequent cancers and causes of death worldwide, despite the huge therapeutic advances in the last decades. The introduction into clinical practice of prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) has...

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Autores principales: Gandini, Annalice, Bauckneht, Matteo, Sofia, Luca, Tomasello, Laura, Fornarini, Giuseppe, Zanardi, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487121/
https://www.ncbi.nlm.nih.gov/pubmed/37685271
http://dx.doi.org/10.3390/diagnostics13172733
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author Gandini, Annalice
Bauckneht, Matteo
Sofia, Luca
Tomasello, Laura
Fornarini, Giuseppe
Zanardi, Elisa
author_facet Gandini, Annalice
Bauckneht, Matteo
Sofia, Luca
Tomasello, Laura
Fornarini, Giuseppe
Zanardi, Elisa
author_sort Gandini, Annalice
collection PubMed
description Prostate cancer still represents one of the most frequent cancers and causes of death worldwide, despite the huge therapeutic advances in the last decades. The introduction into clinical practice of prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) has significantly improved diagnostic capacity, allowing for the identification of lesions previously undetectable. The case we are presenting is about a 90-year-old man affected by metastatic prostate cancer and treated with hormonal therapies. At the second progression, the restaging with PSMA PET/CT pointed out a millimetric cardiac intra-atrial metastasis, on which little/scarce literature data are still available. On one hand, this finding confirms the high sensitivity of this technique, which should be preferred over traditional imaging. On the other hand, it suggests that introducing next-generation imaging into clinical practice may provide novel insights about prostate cancer metastatic spread.
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spelling pubmed-104871212023-09-09 Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT Gandini, Annalice Bauckneht, Matteo Sofia, Luca Tomasello, Laura Fornarini, Giuseppe Zanardi, Elisa Diagnostics (Basel) Interesting Images Prostate cancer still represents one of the most frequent cancers and causes of death worldwide, despite the huge therapeutic advances in the last decades. The introduction into clinical practice of prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) has significantly improved diagnostic capacity, allowing for the identification of lesions previously undetectable. The case we are presenting is about a 90-year-old man affected by metastatic prostate cancer and treated with hormonal therapies. At the second progression, the restaging with PSMA PET/CT pointed out a millimetric cardiac intra-atrial metastasis, on which little/scarce literature data are still available. On one hand, this finding confirms the high sensitivity of this technique, which should be preferred over traditional imaging. On the other hand, it suggests that introducing next-generation imaging into clinical practice may provide novel insights about prostate cancer metastatic spread. MDPI 2023-08-23 /pmc/articles/PMC10487121/ /pubmed/37685271 http://dx.doi.org/10.3390/diagnostics13172733 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Gandini, Annalice
Bauckneht, Matteo
Sofia, Luca
Tomasello, Laura
Fornarini, Giuseppe
Zanardi, Elisa
Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT
title Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT
title_full Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT
title_fullStr Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT
title_full_unstemmed Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT
title_short Cardiac Metastasis from Prostate Cancer: A Case Study Underlying the Crucial Role of the PSMA PET/CT
title_sort cardiac metastasis from prostate cancer: a case study underlying the crucial role of the psma pet/ct
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487121/
https://www.ncbi.nlm.nih.gov/pubmed/37685271
http://dx.doi.org/10.3390/diagnostics13172733
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