Cargando…

Shaping the “hot” immunogenic tumor microenvironment by nanoparticles co‐delivering oncolytic peptide and TGF‐β1 siRNA for boosting checkpoint blockade therapy

Induction of potent immune responses toward tumors remains challenging in cancer immunotherapy, in which it only showed benefits in a minority of patients with “hot” tumors, which possess pre‐existing effector immune cells within the tumor. In this study, we proposed a nanoparticle‐based strategy to...

Descripción completa

Detalles Bibliográficos
Autores principales: Phung, Cao Dai, Nguyen, Bao Loc, Jeong, Jee‐Heon, Chang, Jae‐Hoon, Jin, Sung Giu, Choi, Han‐Gon, Ku, Sae Kwang, Kim, Jong Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487304/
https://www.ncbi.nlm.nih.gov/pubmed/37693065
http://dx.doi.org/10.1002/btm2.10392